Kineret and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Kineret (anakinra), especially for people who are male, 30-39 old, have been taking the drug for 1 - 6 months also take Sulfasalazine, and have Fever.

The phase IV clinical study analyzes which people have Irritability when taking Kineret. It is created by eHealthMe based on reports of 11,092 people who have side effects when taking Kineret from the FDA, and is updated regularly.

What is Kineret?

Kineret has active ingredients of anakinra. It is often used in rheumatoid arthritis. eHealthMe is studying from 11,120 Kineret users. Check the latest studies of Kineret.

What is Irritability?

Irritability is found to be associated with 1,698 drugs and 2,458 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 13, 2026

11,092 people reported to have side effects when taking Kineret.
Among them, 23 people (0.21%) have Irritability.

Among these 23 people:

How long have people been on Kineret when they have Irritability? *

What is the gender of people who have Irritability when taking Kineret? *

female: 47.83 %
male: 52.17 %

What is the age of people who have Irritability when taking Kineret? *

What are other drugs people take besides Kineret? *

What are other side effects people have besides Irritability? *

Headache (pain in head): 10 people, 43.48%
Injection Site Pain: 8 people, 34.78%
Injection Site Erythema (redness at injection site): 7 people, 30.43%
Pain In Extremity: 5 people, 21.74%
Injection Site Pruritus (severe itching at injection site): 5 people, 21.74%
Joint Pain: 5 people, 21.74%
Pain: 5 people, 21.74%
Confusional State: 5 people, 21.74%
Peripheral Swelling: 4 people, 17.39%
Injection Site Reaction: 4 people, 17.39%

What are the existing conditions these people have? *

Fever: 4 people, 17.39%
High Blood Pressure: 2 people, 8.70%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 2 people, 8.70%
Cerebral Venous Thrombosis (clot in brains venous blood system): 2 people, 8.70%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 8.70%
Gastritis (inflammation of stomach): 2 people, 8.70%
Behcet's Syndrome (involves inflammation of the blood vessels): 2 people, 8.70%
Monoclonal Gammopathy: 2 people, 8.70%
Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 8.70%
Pericarditis (inflammation of the pericardium): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Kineret and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Kineret:

Kineret (11,120 reports)

Irritability treatments and more:

Irritability (71,614 reports)

Browse all side effects of Kineret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Irritability (1,698 drugs)

Browse all the conditions that are associated with Irritability:

Irritability (2,458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on anakinra (the active ingredients of Kineret) and Kineret (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.