Klonopin and Pigmentation disorder - a phase IV clinical study of FDA data

Summary:

Pigmentation disorder is reported as a side effect among people who take Klonopin (clonazepam), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Jakafi, and have Polycythaemia vera.

The phase IV clinical study analyzes which people have Pigmentation disorder when taking Klonopin. It is created by eHealthMe based on reports of 59,526 people who have side effects when taking Klonopin from the FDA, and is updated regularly.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

What is Pigmentation disorder?

Pigmentation disorder (disturbances of human skin colour) is found to be associated with 642 drugs and 771 conditions by eHealthMe. Check the latest studies of Pigmentation disorder.

On Jul, 08, 2026

59,526 people reported to have side effects when taking Klonopin.
Among them, 43 people (0.07%) have Pigmentation disorder.

Could Klonopin cause Pigmentation disorder?

Among these 43 people:

How long have people been on Klonopin when they have Pigmentation disorder? *

What is the gender of people who have Pigmentation disorder when taking Klonopin? *

female: 34.78 %
male: 65.22 %

What is the age of people who have Pigmentation disorder when taking Klonopin? *

What are other drugs people take besides Klonopin? *

What are other side effects people have besides Pigmentation disorder? *

Nausea (feeling of having an urge to vomit): 31 people, 72.09%
Joint Pain: 30 people, 69.77%
Weight Increased: 28 people, 65.12%
Fatigue (feeling of tiredness): 23 people, 53.49%
Pain: 23 people, 53.49%
Malaise (a feeling of general discomfort or uneasiness): 23 people, 53.49%
Nausea And Vomiting: 22 people, 51.16%
High Blood Pressure: 22 people, 51.16%
Headache (pain in head): 22 people, 51.16%
Insomnia (sleeplessness): 22 people, 51.16%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 19 people, 44.19%
Tooth Fracture: 15 people, 34.88%
Joint Pain: 11 people, 25.58%
Primary Myelofibrosis (primary disorder of the bone marrow): 8 people, 18.60%
Sleep Disorder: 7 people, 16.28%
Hypersensitivity: 7 people, 16.28%
Pain: 6 people, 13.95%
Nuclear Magnetic Resonance Imaging Brain: 2 people, 4.65%
Bipolar Disorder (mood disorder): 2 people, 4.65%
Depression: 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Klonopin and have Pigmentation disorder?

- Check whether Pigmentation disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Klonopin:

Klonopin (65,112 reports)

Browse all side effects of Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pigmentation disorder:

Pigmentation disorder (642 drugs)

Browse all the conditions that are associated with Pigmentation disorder:

Pigmentation disorder (771 conditions)

Related publications that referenced our studies

McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on clonazepam (the active ingredients of Klonopin) and Klonopin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.