Lacosamide and Facial paralysis - a phase IV clinical study of FDA data

Summary:

Facial paralysis is reported as a side effect among people who take Lacosamide (lacosamide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Rivaroxaban, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Facial paralysis when taking Lacosamide. It is created by eHealthMe based on reports of 16,542 people who have side effects when taking Lacosamide from the FDA, and is updated regularly.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

What is Facial paralysis?

Facial paralysis (loss of function of face muscle) is found to be associated with 663 drugs and 1,149 conditions by eHealthMe. Check the latest studies of Facial paralysis.

On Jul, 22, 2026

16,542 people reported to have side effects when taking Lacosamide.
Among them, 26 people (0.16%) have Facial paralysis.

Could Lacosamide cause Facial paralysis?

Among these 26 people:

How long have people been on Lacosamide when they have Facial paralysis? *

What is the gender of people who have Facial paralysis when taking Lacosamide? *

female: 7.69 %
male: 92.31 %

What is the age of people who have Facial paralysis when taking Lacosamide? *

What are other drugs people take besides Lacosamide? *

What are other side effects people have besides Facial paralysis? *

Speech Impairment (Adult) (inability to speak (adult)): 15 people, 57.69%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 14 people, 53.85%
Drug Level Decreased: 14 people, 53.85%
Antipsychotic Drug Level Increased: 4 people, 15.38%
Fainting (loss of consciousness and postural tone): 4 people, 15.38%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 15.38%
Fall: 3 people, 11.54%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 11.54%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 11.54%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 11.54%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 14 people, 53.85%
Partial Seizures (seizures which affect only a part of the brain at onset): 13 people, 50.00%
High Blood Pressure: 7 people, 26.92%
Petit Mal Epilepsy (absence seizure): 5 people, 19.23%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 11.54%
Bone Marrow Conditioning Regimen: 3 people, 11.54%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.69%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 1 person, 3.85%
Headache (pain in head): 1 person, 3.85%
Complex Partial Seizures (epileptic seizure): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Lacosamide and have Facial paralysis?

- Check whether Facial paralysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lacosamide:

Lacosamide (16,601 reports)

Browse all side effects of Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Facial paralysis:

Facial paralysis (663 drugs)

Browse all the conditions that are associated with Facial paralysis:

Facial paralysis (1,149 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Lacosamide) and Lacosamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.