Lasix and Rectal perforation - a phase IV clinical study of FDA data

Summary:

Rectal perforation is reported as a side effect among people who take Lasix (furosemide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Diovan, and have Gastrointestinal stromal tumor.

The phase IV clinical study analyzes which people have Rectal perforation when taking Lasix. It is created by eHealthMe based on reports of 208,196 people who have side effects when taking Lasix from the FDA, and is updated regularly.

What is Lasix?

Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.

What is Rectal perforation?

Rectal perforation (tear or hole in rectum) is found to be associated with 89 drugs and 194 conditions by eHealthMe. Check the latest studies of Rectal perforation.

On Jul, 16, 2026

208,196 people reported to have side effects when taking Lasix.
Among them, 26 people (0.01%) have Rectal perforation.

Among these 26 people:

How long have people been on Lasix when they have Rectal perforation? *

What is the gender of people who have Rectal perforation when taking Lasix? *

female: 73.08 %
male: 26.92 %

What is the age of people who have Rectal perforation when taking Lasix? *

What are other drugs people take besides Lasix? *

What are other side effects people have besides Rectal perforation? *

Sepsis (a severe blood infection that can lead to organ failure and death): 10 people, 38.46%
Septic Shock (shock due to blood infection): 8 people, 30.77%
Perirectal Abscess: 7 people, 26.92%
Nausea And Vomiting: 6 people, 23.08%
Scrotal Swelling: 6 people, 23.08%
Nausea (feeling of having an urge to vomit): 6 people, 23.08%
Gas Gangrene (bacterial infection that produces gas within tissues): 6 people, 23.08%
Depressed Level Of Consciousness: 6 people, 23.08%
Necrotising Fasciitis (an uncommon life-threatening soft-tissue infection): 6 people, 23.08%
Fever: 6 people, 23.08%

What are the existing conditions these people have? *

Gastrointestinal Stromal Tumor: 6 people, 23.08%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 15.38%
Hyperkalemia (damage to or disease of the kidney): 3 people, 11.54%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 7.69%
Cytomegalovirus Infection: 2 people, 7.69%
Heart Attack: 2 people, 7.69%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 7.69%
Rectal Cancer (cancer of rectum): 2 people, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 7.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Lasix and have Rectal perforation?

- Check whether Rectal perforation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lasix:

Lasix (210,439 reports)

Browse all side effects of Lasix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal perforation:

Rectal perforation (89 drugs)

Browse all the conditions that are associated with Rectal perforation:

Rectal perforation (194 conditions)

Related publications that referenced our studies

Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .

How the study uses the data?

The study uses data from the FDA. It is based on furosemide (the active ingredients of Lasix) and Lasix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.