Lenalidomide and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Lenalidomide (lenalidomide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Dexamethasone, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Lenalidomide. It is created by eHealthMe based on reports of 52,873 people who have side effects when taking Lenalidomide from the FDA, and is updated regularly.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,043 drugs and 1,786 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

52,873 people reported to have side effects when taking Lenalidomide.
Among them, 98 people (0.19%) have Clostridium difficile colitis.

Could Lenalidomide cause Clostridium difficile colitis?

Among these 98 people:

How long have people been on Lenalidomide when they have Clostridium difficile colitis? *

What is the gender of people who have Clostridium difficile colitis when taking Lenalidomide? *

female: 48.35 %
male: 51.65 %

What is the age of people who have Clostridium difficile colitis when taking Lenalidomide? *

What are other drugs people take besides Lenalidomide? *

What are other side effects people have besides Clostridium difficile colitis? *

Sepsis (a severe blood infection that can lead to organ failure and death): 26 people, 26.53%
Pneumonia: 23 people, 23.47%
Colitis (inflammation of colon): 17 people, 17.35%
Thrombocytopenia (decrease of platelets in blood): 17 people, 17.35%
Cerebral Toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii): 17 people, 17.35%
Drug Ineffective: 16 people, 16.33%
Neuropathy Peripheral (surface nerve damage): 15 people, 15.31%
Multiple Myeloma (cancer of the plasma cells): 14 people, 14.29%
Pseudomembranous Colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon): 14 people, 14.29%
Lymphopenia (an abnormally low level of lymphocytes in the blood): 14 people, 14.29%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 74 people, 75.51%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 12 people, 12.24%
Bone Marrow Conditioning Regimen: 11 people, 11.22%
Graft Versus Host Disease In Liver (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the liver): 6 people, 6.12%
Hypotension (abnormally low blood pressure): 5 people, 5.10%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 4 people, 4.08%
Amyloidosis (a tumour within which amyloid is produced): 4 people, 4.08%
High Blood Pressure: 4 people, 4.08%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 4.08%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 4.08%

* Approximation only. Some reports may have incomplete information.

Do you take Lenalidomide and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lenalidomide:

Lenalidomide (52,881 reports)

Browse all side effects of Lenalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,043 drugs)

Browse all the conditions that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,786 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lenalidomide (the active ingredients of Lenalidomide) and Lenalidomide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.