Letrozole and Heavy or prolong menstrual bleeding - a phase IV clinical study of FDA data

Summary:

Heavy or prolong menstrual bleeding is reported as a side effect among people who take Letrozole (letrozole), especially for people who are 50-59 old, also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Heavy or prolong menstrual bleeding when taking Letrozole. It is created by eHealthMe based on reports of 53,470 people who have side effects when taking Letrozole from the FDA, and is updated regularly.

What is Letrozole?

Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.

What is Heavy or prolong menstrual bleeding?

Heavy or prolong menstrual bleeding is found to be associated with 749 drugs and 1,264 conditions by eHealthMe. Check the latest studies of Heavy or prolong menstrual bleeding.

On Jul, 17, 2026

53,470 people reported to have side effects when taking Letrozole.
Among them, 16 people (0.03%) have Heavy or prolong menstrual bleeding.

Could Letrozole cause Heavy or prolong menstrual bleeding?

Among these 16 people:

What is the age of people who have Heavy or prolong menstrual bleeding when taking Letrozole? *

What are other drugs people take besides Letrozole? *

What are other side effects people have besides Heavy or prolong menstrual bleeding? *

Therapeutic Response Decreased (less preventive response): 12 people, 75.00%
Synovitis (inflammation of the synovial membrane): 12 people, 75.00%
Depression: 12 people, 75.00%
Drug Ineffective: 12 people, 75.00%
Joint Pain: 12 people, 75.00%
Drug Intolerance (drug sensitivity): 12 people, 75.00%
Breast Cancer Female: 2 people, 12.50%
Vaginal Bleeding Between Periods: 1 person, 6.25%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 6.25%
Breast Pain: 1 person, 6.25%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 75.00%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 3 people, 18.75%
Urinary Tract Infection: 1 person, 6.25%
Stress And Anxiety: 1 person, 6.25%
Pain: 1 person, 6.25%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
Infertility: 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Letrozole and have Heavy or prolong menstrual bleeding?

- Check whether Heavy or prolong menstrual bleeding is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Letrozole:

Letrozole (54,125 reports)

Browse all side effects of Letrozole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heavy or prolong menstrual bleeding:

Heavy or prolong menstrual bleeding (749 drugs)

Browse all the conditions that are associated with Heavy or prolong menstrual bleeding:

Heavy or prolong menstrual bleeding (1,264 conditions)

Related publications that referenced our studies

Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on letrozole (the active ingredients of Letrozole) and Letrozole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.