Letrozole and Hernia - a phase IV clinical study of FDA data
Summary:
Hernia is reported as a side effect among people who take Letrozole (letrozole), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Ibrance, and have Metastases to bone.
The phase IV clinical study analyzes which people have Hernia when taking Letrozole. It is created by eHealthMe based on reports of 53,470 people who have side effects when taking Letrozole from the FDA, and is updated regularly.
What is Letrozole?
Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.
What is Hernia?
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle) is found to be associated with 1,306 drugs and 1,497 conditions by eHealthMe. Check the latest studies of Hernia.
53,470 people reported to have side effects when taking Letrozole.
Among them, 64 people (0.12%) have Hernia.

Among these 64 people:
How long have people been on Letrozole when they have Hernia? *
- < 1 month: 0.0 %
- 1 - 6 months: 78.95 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 21.05 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hernia when taking Letrozole? *
- female: 98.36 %
- male: 1.64 %
What is the age of people who have Hernia when taking Letrozole? *
- 0-1: 2.38 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 4.76 %
- 40-49: 9.52 %
- 50-59: 2.38 %
- 60+: 80.95 %
What are other drugs people take besides Letrozole? *
- Ibrance: 26 people, 40.62%
- Kisqali: 19 people, 29.69%
- Xgeva: 6 people, 9.38%
- Palbociclib: 5 people, 7.81%
- Humira: 5 people, 7.81%
- Vitamin D3: 4 people, 6.25%
- Clexane: 4 people, 6.25%
- Ribociclib: 3 people, 4.69%
- Vitamin D: 3 people, 4.69%
- Vancomycin Hydrochloride: 3 people, 4.69%
What are other side effects people have besides Hernia? *
- Nasopharyngitis (inflammation of the nasopharynx): 18 people, 28.12%
- Ascites (accumulation of fluid in the abdominal cavity): 17 people, 26.56%
- Gallstones (stone formation by bile component): 16 people, 25.00%
- Liver Function Test Abnormal: 15 people, 23.44%
- Hepatic Steatosis (fatty liver disease): 15 people, 23.44%
- Transaminases Increased: 14 people, 21.88%
- Blood Alkaline Phosphatase Increased: 14 people, 21.88%
- Blood Bilirubin Increased: 14 people, 21.88%
- Hepatic Enzyme Increased: 14 people, 21.88%
- Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 14 people, 21.88%
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 8 people, 12.50%
- Pain: 6 people, 9.38%
- Haemodilution (increase in the volume of plasma in relation to red blood cells): 6 people, 9.38%
- Breast Cancer Female: 4 people, 6.25%
- Tumor: 3 people, 4.69%
- Metastases To Liver (cancer spreads to liver): 3 people, 4.69%
- Pleural Effusion (water on the lungs): 3 people, 4.69%
- Metastases To Peritoneum (cancer spreads to peritoneum): 3 people, 4.69%
- Pericardial Effusion (fluid around the heart): 3 people, 4.69%
- Neck Pain: 2 people, 3.12%
* Approximation only. Some reports may have incomplete information.
Do you take Letrozole and have Hernia?
- Check whether Hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Letrozole:
- Letrozole (54,125 reports)
Hernia treatments and more:
- Hernia (31,430 reports)
How severe was Hernia and when was it recovered:
Expand to all the drugs that have ingredients of letrozole:
- Hernia and drugs with ingredients of letrozole (80 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Letrozole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hernia:
- Hernia (1,306 drugs)
Browse all the conditions that are associated with Hernia:
- Hernia (1,497 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on letrozole (the active ingredients of Letrozole) and Letrozole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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