Leucovorin calcium and Broken bone - a phase IV clinical study of FDA data

Summary:

Broken bone is reported as a side effect among people who take Leucovorin calcium (leucovorin calcium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Fluorouracil, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Broken bone when taking Leucovorin calcium. It is created by eHealthMe based on reports of 24,555 people who have side effects when taking Leucovorin calcium from the FDA, and is updated regularly.

What is Leucovorin calcium?

Leucovorin calcium has active ingredients of leucovorin calcium. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,650 Leucovorin calcium users. Check the latest studies of Leucovorin calcium.

What is Broken bone?

Broken bone is found to be associated with 1,305 drugs and 1,492 conditions by eHealthMe. Check the latest studies of Broken bone.

On Jul, 20, 2026

24,555 people reported to have side effects when taking Leucovorin calcium.
Among them, 12 people (0.05%) have Broken bone.

Could Leucovorin calcium cause Broken bone?

Among these 12 people:

How long have people been on Leucovorin calcium when they have Broken bone? *

What is the gender of people who have Broken bone when taking Leucovorin calcium? *

female: 50 %
male: 50 %

What is the age of people who have Broken bone when taking Leucovorin calcium? *

What are other drugs people take besides Leucovorin calcium? *

What are other side effects people have besides Broken bone? *

Fall: 8 people, 66.67%
Weakness: 5 people, 41.67%
Nausea (feeling of having an urge to vomit): 4 people, 33.33%
Muscle Spasms (muscle contraction): 4 people, 33.33%
Nausea And Vomiting: 4 people, 33.33%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 25.00%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 25.00%
Muscle Aches (muscle pain): 3 people, 25.00%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 25.00%
Movement - Uncoordinated: 3 people, 25.00%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 25.00%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 16.67%
Colon Cancer: 2 people, 16.67%
Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 8.33%
Insomnia (sleeplessness): 1 person, 8.33%
Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Leucovorin calcium and have Broken bone?

- Check whether Broken bone is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Leucovorin calcium:

Leucovorin calcium (24,650 reports)

Broken bone treatments and more:

Broken bone (35,552 reports)

Browse all side effects of Leucovorin calcium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Broken bone:

Broken bone (1,305 drugs)

Browse all the conditions that are associated with Broken bone:

Broken bone (1,492 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on leucovorin calcium (the active ingredients of Leucovorin calcium) and Leucovorin calcium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.