Leukine and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Leukine (sargramostim), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zofran, and have Malignant melanoma.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Leukine. It is created by eHealthMe based on reports of 2,173 people who have side effects when taking Leukine from the FDA, and is updated regularly.

What is Leukine?

Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,887 drugs and 2,613 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.



On Jul, 08, 2026

2,173 people reported to have side effects when taking Leukine.
Among them, 13 people (0.6%) have Intestinal obstruction.

Could Leukine cause Intestinal obstruction?

Among these 13 people:

How long have people been on Leukine when they have Intestinal obstruction? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Intestinal obstruction when taking Leukine? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Intestinal obstruction when taking Leukine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 20 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 30 %
  • 60+: 50 %

What are other drugs people take besides Leukine? *

  1. Zofran: 6 people, 46.15%
  2. Nexium: 4 people, 30.77%
  3. Celexa: 3 people, 23.08%
  4. Fosamax: 3 people, 23.08%
  5. Flonase: 3 people, 23.08%
  6. Phenergan: 3 people, 23.08%
  7. Colace: 3 people, 23.08%
  8. Prilosec: 2 people, 15.38%
  9. Flovent: 2 people, 15.38%
  10. Warfarin Sodium: 2 people, 15.38%

What are other side effects people have besides Intestinal obstruction? *

  1. Fever: 6 people, 46.15%
  2. Weight Decreased: 4 people, 30.77%
  3. Anaemia (lack of blood): 4 people, 30.77%
  4. Fainting (loss of consciousness and postural tone): 4 people, 30.77%
  5. Hyperkalemia (damage to or disease of the kidney): 4 people, 30.77%
  6. Small Intestinal Obstruction (blockage in small intestine): 4 people, 30.77%
  7. Diarrhea: 4 people, 30.77%
  8. Hypokalemia (low potassium): 4 people, 30.77%
  9. Constipation: 4 people, 30.77%
  10. Computerised Tomogram Abnormal: 4 people, 30.77%

What are the existing conditions these people have? *

  1. Malignant Melanoma (skin cancer rises from melancytes): 4 people, 30.77%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%
  3. Weight Decreased: 1 person, 7.69%
  4. Prostate Cancer: 1 person, 7.69%
  5. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Leukine and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Leukine:

Intestinal obstruction treatments and more:

How severe was Intestinal obstruction and when was it recovered:

Expand to all the drugs that have ingredients of sargramostim:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Leukine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Browse all the conditions that are associated with Intestinal obstruction:


How the study uses the data?

The study uses data from the FDA. It is based on sargramostim (the active ingredients of Leukine) and Leukine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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