Levaquin and Formication - a phase IV clinical study of FDA data

Summary:

Formication is reported as a side effect among people who take Levaquin (levofloxacin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Osteoporosis.

The phase IV clinical study analyzes which people have Formication when taking Levaquin. It is created by eHealthMe based on reports of 54,998 people who have side effects when taking Levaquin from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Formication?

Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin) is found to be associated with 567 drugs and 915 conditions by eHealthMe. Check the latest studies of Formication.



On Sep, 11, 2025

54,998 people reported to have side effects when taking Levaquin.
Among them, 46 people (0.08%) have Formication.

Could Levaquin cause Formication?

Among these 46 people:

How long have people been on Levaquin when they have Formication? *

  • < 1 month: 94.44 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 5.56 %

What is the gender of people who have Formication when taking Levaquin? *

  • female: 80 %
  • male: 20 %

What is the age of people who have Formication when taking Levaquin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.78 %
  • 20-29: 0.0 %
  • 30-39: 19.44 %
  • 40-49: 30.56 %
  • 50-59: 13.89 %
  • 60+: 33.33 %

What are other drugs people take besides Levaquin? *

  1. Fluconazole: 7 people, 15.22%
  2. Coumadin: 7 people, 15.22%
  3. Lorazepam: 5 people, 10.87%
  4. Synthroid: 5 people, 10.87%
  5. Boniva: 5 people, 10.87%
  6. Oxycontin: 4 people, 8.70%
  7. Zometa: 4 people, 8.70%
  8. Lisinopril: 4 people, 8.70%
  9. Erythromycin: 4 people, 8.70%
  10. Calcium: 4 people, 8.70%

What are other side effects people have besides Formication? *

  1. Insomnia (sleeplessness): 20 people, 43.48%
  2. Stress And Anxiety: 18 people, 39.13%
  3. Pain In Extremity: 16 people, 34.78%
  4. Weakness: 16 people, 34.78%
  5. Burning Sensation: 14 people, 30.43%
  6. Fatigue (feeling of tiredness): 14 people, 30.43%
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 14 people, 30.43%
  8. Dyspnea (difficult or laboured breathing): 12 people, 26.09%
  9. Joint Pain: 12 people, 26.09%
  10. Confusional State: 10 people, 21.74%

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 4 people, 8.70%
  2. Osteoporosis (bones weak and more likely to break): 4 people, 8.70%
  3. Oropharyngeal Pain: 3 people, 6.52%
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 6.52%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 4.35%
  6. Pain: 2 people, 4.35%
  7. Cellulitis (infection under the skin): 2 people, 4.35%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 2.17%
  9. Bipolar Disorder (mood disorder): 1 person, 2.17%
  10. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Levaquin and have Formication?

- Check whether Formication is associated with a drug or a condition
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- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levaquin:

Formication treatments and more:

How severe was Formication and when was it recovered:

Expand to all the drugs that have ingredients of levofloxacin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Formication:

Browse all the conditions that are associated with Formication:

Drugs similar to Levaquin and Formication :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levofloxacin (the active ingredients of Levaquin) and Levaquin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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