Levaquin and Skeletal injury - a phase IV clinical study of FDA data

Summary:

Skeletal injury is reported as a side effect among people who take Levaquin (levofloxacin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Urinary tract infection.

The phase IV clinical study analyzes which people have Skeletal injury when taking Levaquin. It is created by eHealthMe based on reports of 54,998 people who have side effects when taking Levaquin from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Skeletal injury?

Skeletal injury (bone and supporting muscle injury) is found to be associated with 445 drugs and 391 conditions by eHealthMe. Check the latest studies of Skeletal injury.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

54,998 people reported to have side effects when taking Levaquin.
Among them, 45 people (0.08%) have Skeletal injury.

Among these 45 people:

How long have people been on Levaquin when they have Skeletal injury? *

What is the gender of people who have Skeletal injury when taking Levaquin? *

female: 46.51 %
male: 53.49 %

What is the age of people who have Skeletal injury when taking Levaquin? *

What are other drugs people take besides Levaquin? *

What are other side effects people have besides Skeletal injury? *

Pain: 36 people, 80.00%
Stress And Anxiety: 26 people, 57.78%
Oedema Peripheral (superficial swelling): 24 people, 53.33%
Gait Disturbance: 23 people, 51.11%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 22 people, 48.89%
Fatigue (feeling of tiredness): 22 people, 48.89%
Fall: 21 people, 46.67%
Back Pain: 21 people, 46.67%
Constipation: 21 people, 46.67%
Muscle Spasms (muscle contraction): 20 people, 44.44%

What are the existing conditions these people have? *

Urinary Tract Infection: 14 people, 31.11%
Prostate Cancer Metastatic: 13 people, 28.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 24.44%
Pain: 10 people, 22.22%
Mixed Incontinence (a combination of stress and urge incontinence): 7 people, 15.56%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 7 people, 15.56%
Allergic Rhinitis: 7 people, 15.56%
Restless Leg Syndrome (a powerful urge to move your legs): 7 people, 15.56%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 15.56%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 15.56%

* Approximation only. Some reports may have incomplete information.

Do you take Levaquin and have Skeletal injury?

- Check whether Skeletal injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levaquin:

Levaquin (56,638 reports)

Skeletal injury treatments and more:

Skeletal injury (25,409 reports)

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skeletal injury:

Skeletal injury (445 drugs)

Browse all the conditions that are associated with Skeletal injury:

Skeletal injury (391 conditions)

Related publications that referenced our studies

Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on levofloxacin (the active ingredients of Levaquin) and Levaquin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.