Levaquin and Uc - a phase IV clinical study of FDA data

Summary:

Uc is reported as a side effect among people who take Levaquin (levofloxacin), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Asacol, and have Systemic lupus erythematosus.

The phase IV clinical study analyzes which people have Uc when taking Levaquin. It is created by eHealthMe based on reports of 54,998 people who have side effects when taking Levaquin from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Uc?

Uc is found to be associated with 1,302 drugs and 2,024 conditions by eHealthMe. Check the latest studies of Uc.

On Nov, 14, 2025

54,998 people reported to have side effects when taking Levaquin.
Among them, 118 people (0.21%) have Uc.

Among these 118 people:

* Approximation only. Some reports may have incomplete information.

Do you take Levaquin and have Uc?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levaquin:

Levaquin (56,638 reports)

Uc treatments and more:

Uc (188,233 reports)

How severe was Uc and when was it recovered:

Uc in Levaquin

Expand to all the drugs that have ingredients of levofloxacin:

Uc and drugs with ingredients of levofloxacin (153 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Levaquin side effects:

Levaquin side effect: Joint pain (4,427 reports)
Levaquin side effect: Neuropathy peripheral (surface nerve damage) (3,741 reports)

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Uc:

Prednisone side effect: Uc (9,847 reports)
Accutane side effect: Uc (9,193 reports)
Humira side effect: Uc (7,275 reports)
Mesalamine side effect: Uc (4,332 reports)
Remicade side effect: Uc (4,272 reports)
Entyvio side effect: Uc (2,464 reports)
Methotrexate side effect: Uc (2,260 reports)
Asacol side effect: Uc (1,994 reports)
Pentasa side effect: Uc (1,864 reports)
Pantoprazole side effect: Uc (1,709 reports)

Browse all the drugs that are associated with Uc:

Uc (1,302 drugs)

Common conditions associated with Uc:

Uc: 9,507 reports
Acne aggravated: 6,047 reports
Acne vulgaris: 6,041 reports
Ulcerative colitis: 4,538 reports
Inflammatory bowel disease - ulcerative colitis: 4,525 reports
Colitis ulcerative: 3,853 reports
Crohn's disease aggravated: 1,997 reports
Hypertension: 1,314 reports
Rheumatoid arthritis: 1,295 reports
Ms hug: 765 reports

Browse all the conditions that are associated with Uc:

Uc (2,024 conditions)

Drugs similar to Levaquin and Uc :

Related publications that referenced our studies

Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on levofloxacin (the active ingredients of Levaquin) and Levaquin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.