Levothroid and Crohn's disease - a phase IV clinical study of FDA data

Summary:

Crohn's disease is reported as a side effect among people who take Levothroid (levothyroxine sodium), especially for people who are female, 60+ old, also take Humira, and have Osteoporosis.

The phase IV clinical study analyzes which people have Crohn's disease when taking Levothroid. It is created by eHealthMe based on reports of 8,088 people who have side effects when taking Levothroid from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

What is Crohn's disease?

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract) is found to be associated with 1,351 drugs and 2,076 conditions by eHealthMe. Check the latest studies of Crohn's disease.



On Jul, 14, 2026

8,088 people reported to have side effects when taking Levothroid.
Among them, 13 people (0.16%) have Crohn's disease.

Could Levothroid cause Crohn's disease?

Among these 13 people:

What is the gender of people who have Crohn's disease when taking Levothroid? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Crohn's disease when taking Levothroid? *

  • 0-1: 0.0 %
  • 2-9: 9.09 %
  • 10-19: 9.09 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 18.18 %
  • 60+: 54.55 %

What are other drugs people take besides Levothroid? *

  1. Norvasc: 5 people, 38.46%
  2. Humira: 5 people, 38.46%
  3. Lopressor: 3 people, 23.08%
  4. Benicar: 2 people, 15.38%
  5. Azathioprine: 2 people, 15.38%
  6. Prevacid: 2 people, 15.38%
  7. Prilosec: 2 people, 15.38%
  8. Entocort Ec: 2 people, 15.38%
  9. Flomax: 2 people, 15.38%
  10. Forteo: 2 people, 15.38%

What are other side effects people have besides Crohn's disease? *

  1. Insomnia (sleeplessness): 2 people, 15.38%
  2. Depression: 2 people, 15.38%
  3. Infection: 2 people, 15.38%
  4. Irritable Bowel Syndrome: 2 people, 15.38%
  5. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 2 people, 15.38%
  6. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  7. Head Injury: 2 people, 15.38%
  8. Fistula (an abnormal connection or passageway between two): 2 people, 15.38%
  9. Fatigue (feeling of tiredness): 2 people, 15.38%
  10. Drug Ineffective: 2 people, 15.38%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 3 people, 23.08%
  2. High Blood Pressure: 2 people, 15.38%
  3. Sleep Disorder: 2 people, 15.38%
  4. Pain: 2 people, 15.38%
  5. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  6. Diabetes: 2 people, 15.38%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 7.69%
  8. Anaemia (lack of blood): 1 person, 7.69%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.69%
  10. Cardiac Disorder: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Levothroid and have Crohn's disease?

- Check whether Crohn's disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothroid:

Crohn's disease treatments and more:

How severe was Crohn's disease and when was it recovered:

Expand to all the drugs that have ingredients of levothyroxine sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Crohn's disease:

Browse all the conditions that are associated with Crohn's disease:


How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothroid) and Levothroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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