Levothroid and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Levothroid (levothyroxine sodium), especially for people who are female, 50-59 old, also take Synthroid, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Levothroid. It is created by eHealthMe based on reports of 8,088 people who have side effects when taking Levothroid from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,973 Levothroid users. Check the latest studies of Levothroid.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 747 drugs and 624 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Sep, 22, 2025

8,088 people reported to have side effects when taking Levothroid.
Among them, 10 people (0.12%) have Diastolic dysfunction.

Could Levothroid cause Diastolic dysfunction?

Among these 10 people:

What is the gender of people who have Diastolic dysfunction when taking Levothroid? *

female: 90 %
male: 10 %

What is the age of people who have Diastolic dysfunction when taking Levothroid? *

What are other drugs people take besides Levothroid? *

What are other side effects people have besides Diastolic dysfunction? *

Cardiac Failure Congestive: 4 people, 40.00%
Dyspnea (difficult or laboured breathing): 4 people, 40.00%
Stress And Anxiety: 3 people, 30.00%
Nausea (feeling of having an urge to vomit): 3 people, 30.00%
Pleural Effusion (water on the lungs): 3 people, 30.00%
Arrhythmias (irregular heartbeat): 3 people, 30.00%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 30.00%
High Blood Pressure: 3 people, 30.00%
Enlarged Heart: 2 people, 20.00%
Hypotension (abnormally low blood pressure): 2 people, 20.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 2 people, 20.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 20.00%
Sleep Disorder: 1 person, 10.00%
High Blood Pressure: 1 person, 10.00%
Blood Pressure Abnormal: 1 person, 10.00%
Breast Cancer: 1 person, 10.00%
Breast Cancer Metastatic: 1 person, 10.00%
Cardiac Failure: 1 person, 10.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 10.00%
Claustrophobia (fear of having no escape and being closed in small spaces): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Levothroid and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothroid:

Levothroid (8,973 reports)

Diastolic dysfunction treatments and more:

Diastolic dysfunction (4,665 reports)

How severe was Diastolic dysfunction and when was it recovered:

Diastolic dysfunction in Levothroid

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (747 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (624 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothroid) and Levothroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.