Levothyroxine sodium and Empyema - a phase IV clinical study of FDA data

Summary:

Empyema is reported as a side effect among people who take Levothyroxine sodium (levothyroxine sodium), especially for people who are male, 60+ old, also take Prednisolone, and have Osteoporosis.

The phase IV clinical study analyzes which people have Empyema when taking Levothyroxine sodium. It is created by eHealthMe based on reports of 122,907 people who have side effects when taking Levothyroxine sodium from the FDA, and is updated regularly.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,812 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

What is Empyema?

Empyema (collection of pus in a cavity in the body) is found to be associated with 361 drugs and 512 conditions by eHealthMe. Check the latest studies of Empyema.



On Jul, 08, 2026

122,907 people reported to have side effects when taking Levothyroxine sodium.
Among them, 23 people (0.02%) have Empyema.

Could Levothyroxine sodium cause Empyema?

Among these 23 people:

What is the gender of people who have Empyema when taking Levothyroxine sodium? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Empyema when taking Levothyroxine sodium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 35.71 %
  • 60+: 64.29 %

What are other drugs people take besides Levothyroxine sodium? *

  1. Forteo: 5 people, 21.74%
  2. Pantoprazole Sodium: 5 people, 21.74%
  3. Prednisolone: 5 people, 21.74%
  4. Atenolol: 4 people, 17.39%
  5. Ibuprofen: 4 people, 17.39%
  6. Cisplatin: 3 people, 13.04%
  7. Lumigan: 3 people, 13.04%
  8. Omeprazole: 3 people, 13.04%
  9. Loperamide Hydrochloride: 3 people, 13.04%
  10. Pantoprazole: 3 people, 13.04%

What are other side effects people have besides Empyema? *

  1. Pleural Effusion (water on the lungs): 6 people, 26.09%
  2. Pneumonia: 6 people, 26.09%
  3. Swelling: 4 people, 17.39%
  4. Wound Infection Staphylococcal: 3 people, 13.04%
  5. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 13.04%
  6. Pain: 3 people, 13.04%
  7. Osteolysis (dissolution of bone): 3 people, 13.04%
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 13.04%
  9. Osteitis (a general term for inflammation of bone): 3 people, 13.04%
  10. Breathing Sounds - Abnormal (Stridor): 3 people, 13.04%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 5 people, 21.74%
  2. Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 3 people, 13.04%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 13.04%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 13.04%
  5. Gastric Disorder (disease of stomach): 3 people, 13.04%
  6. Depression: 3 people, 13.04%
  7. Asthma: 3 people, 13.04%
  8. Renal Cell Carcinoma (a kidney cancer): 2 people, 8.70%
  9. Organising Pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue): 2 people, 8.70%
  10. Eye Disorder: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Levothyroxine sodium and have Empyema?

- Check whether Empyema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothyroxine sodium:

Empyema treatments and more:

How severe was Empyema and when was it recovered:

Expand to all the drugs that have ingredients of levothyroxine sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levothyroxine sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Empyema:

Browse all the conditions that are associated with Empyema:


How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothyroxine sodium) and Levothyroxine sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: