Levothyroxine sodium and Injection site vesicles - a phase IV clinical study of FDA data

Summary:

Injection site vesicles is reported as a side effect among people who take Levothyroxine sodium (levothyroxine sodium), especially for people who are female, 60+ old, also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Injection site vesicles when taking Levothyroxine sodium. It is created by eHealthMe based on reports of 122,907 people who have side effects when taking Levothyroxine sodium from the FDA, and is updated regularly.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,813 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

What is Injection site vesicles?

Injection site vesicles (fluid- or air-filled cavity or sac at injection site) is found to be associated with 299 drugs and 387 conditions by eHealthMe. Check the latest studies of Injection site vesicles.

On Aug, 09, 2026

122,907 people reported to have side effects when taking Levothyroxine sodium.
Among them, 27 people (0.02%) have Injection site vesicles.

Could Levothyroxine sodium cause Injection site vesicles?

Among these 27 people:

What is the gender of people who have Injection site vesicles when taking Levothyroxine sodium? *

female: 96 %
male: 4 %

What is the age of people who have Injection site vesicles when taking Levothyroxine sodium? *

What are other drugs people take besides Levothyroxine sodium? *

What are other side effects people have besides Injection site vesicles? *

Injection Site Pruritus (severe itching at injection site): 10 people, 37.04%
Injection Site Erythema (redness at injection site): 10 people, 37.04%
Joint Pain: 8 people, 29.63%
Injection Site Swelling: 8 people, 29.63%
Chest Pain: 6 people, 22.22%
Injection Site Pain: 5 people, 18.52%
Lower Respiratory Tract Infection: 5 people, 18.52%
Drug Ineffective: 5 people, 18.52%
Injection Site Reaction: 5 people, 18.52%
Quality Of Life Decreased: 5 people, 18.52%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 66.67%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 7.41%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 7.41%
Arthritis Enteropathic (form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease): 2 people, 7.41%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 3.70%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 3.70%
Nasal Polyps (masses that develop in the lining of the nose): 1 person, 3.70%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 3.70%
Gastrointestinal Stoma Complication (complication of an opening surgically made in digestive tract): 1 person, 3.70%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Levothyroxine sodium and have Injection site vesicles?

- Check whether Injection site vesicles is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothyroxine sodium:

Levothyroxine sodium (129,813 reports)

Browse all side effects of Levothyroxine sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site vesicles:

Injection site vesicles (299 drugs)

Browse all the conditions that are associated with Injection site vesicles:

Injection site vesicles (387 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothyroxine sodium) and Levothyroxine sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.