Levothyroxine sodium and Urine abnormality - a phase IV clinical study of FDA data

Summary:

Urine abnormality is reported as a side effect among people who take Levothyroxine sodium (levothyroxine sodium), especially for people who are female, 60+ old, also take Tegsedi, and have Hereditary neuropathic amyloidosis.

The phase IV clinical study analyzes which people have Urine abnormality when taking Levothyroxine sodium. It is created by eHealthMe based on reports of 122,907 people who have side effects when taking Levothyroxine sodium from the FDA, and is updated regularly.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,812 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

What is Urine abnormality?

Urine abnormality is found to be associated with 534 drugs and 574 conditions by eHealthMe. Check the latest studies of Urine abnormality.

On Jul, 27, 2026

122,907 people reported to have side effects when taking Levothyroxine sodium.
Among them, 51 people (0.04%) have Urine abnormality.

Could Levothyroxine sodium cause Urine abnormality?

Among these 51 people:

What is the gender of people who have Urine abnormality when taking Levothyroxine sodium? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Urine abnormality when taking Levothyroxine sodium? *

What are other drugs people take besides Levothyroxine sodium? *

What are other side effects people have besides Urine abnormality? *

White Blood Cells Urine Positive: 19 people, 37.25%
Bacterial Test Positive: 15 people, 29.41%
Glomerular Filtration Rate Decreased: 14 people, 27.45%
Protein Urine Present: 14 people, 27.45%
Dyspnea (difficult or laboured breathing): 14 people, 27.45%
Urine Protein/creatinine Ratio Increased: 12 people, 23.53%
Pain: 12 people, 23.53%
Urine Leukocyte Esterase Positive: 12 people, 23.53%
Crystal Urine Present: 11 people, 21.57%
Red Blood Cells Urine Positive: 10 people, 19.61%

What are the existing conditions these people have? *

Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 13 people, 25.49%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 5 people, 9.80%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 7.84%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.84%
Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 4 people, 7.84%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 3.92%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 3.92%
Depression: 2 people, 3.92%
Hair Loss: 2 people, 3.92%
Uterine Leiomyosarcoma (uterus cancer of smooth muscle connective tissue): 2 people, 3.92%

* Approximation only. Some reports may have incomplete information.

Do you take Levothyroxine sodium and have Urine abnormality?

- Check whether Urine abnormality is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Levothyroxine sodium:

Levothyroxine sodium (129,812 reports)

Browse all side effects of Levothyroxine sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urine abnormality:

Urine abnormality (534 drugs)

Browse all the conditions that are associated with Urine abnormality:

Urine abnormality (574 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Levothyroxine sodium) and Levothyroxine sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.