Lialda and Peptic ulcer aggravated - a phase IV clinical study of FDA data

Summary:

Peptic ulcer aggravated is reported as a side effect among people who take Lialda (mesalamine), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Humira, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Peptic ulcer aggravated when taking Lialda. It is created by eHealthMe based on reports of 9,821 people who have side effects when taking Lialda from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Peptic ulcer aggravated?

Peptic ulcer aggravated is found to be associated with 1,494 drugs and 548 conditions by eHealthMe. Check the latest studies of Peptic ulcer aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

9,821 people reported to have side effects when taking Lialda.
Among them, 23 people (0.23%) have Peptic ulcer aggravated.

Could Lialda cause Peptic ulcer aggravated?

Among these 23 people:

How long have people been on Lialda when they have Peptic ulcer aggravated? *

What is the gender of people who have Peptic ulcer aggravated when taking Lialda? *

female: 60 %
male: 40 %

What is the age of people who have Peptic ulcer aggravated when taking Lialda? *

What are other drugs people take besides Lialda? *

What are other side effects people have besides Peptic ulcer aggravated? *

Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 5 people, 21.74%
Anaemia (lack of blood): 5 people, 21.74%
Pneumonia: 4 people, 17.39%
Depression: 4 people, 17.39%
Pain In Extremity: 4 people, 17.39%
Hypotension (abnormally low blood pressure): 3 people, 13.04%
Pain: 3 people, 13.04%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 13.04%
Pancreatitis (inflammation of pancreas): 3 people, 13.04%
Oesophageal Candidiasis (fungal infection of oesophagus): 3 people, 13.04%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 34.78%
High Blood Pressure: 6 people, 26.09%
High Blood Cholesterol: 6 people, 26.09%
Diabetes: 4 people, 17.39%
Pain: 4 people, 17.39%
Thyroid Diseases: 3 people, 13.04%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 13.04%
Nerve Injury: 2 people, 8.70%
Insomnia (sleeplessness): 2 people, 8.70%
Blood Pressure Abnormal: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Lialda and have Peptic ulcer aggravated?

- Check whether Peptic ulcer aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lialda:

Lialda (10,199 reports)

Browse all side effects of Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (1,495 drugs)

Browse all the conditions that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (548 conditions)

Related publications that referenced our studies

Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Lialda) and Lialda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.