Lidocaine and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Lidocaine (lidocaine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Levaquin, and have Nausea.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Lidocaine. It is created by eHealthMe based on reports of 27,239 people who have side effects when taking Lidocaine from the FDA, and is updated regularly.

What is Lidocaine?

Lidocaine has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 27,555 Lidocaine users. Check the latest studies of Lidocaine.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 645 drugs and 807 conditions by eHealthMe. Check the latest studies of Hypernatraemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

27,239 people reported to have side effects when taking Lidocaine.
Among them, 37 people (0.14%) have Hypernatraemia.

Among these 37 people:

How long have people been on Lidocaine when they have Hypernatraemia? *

What is the gender of people who have Hypernatraemia when taking Lidocaine? *

female: 72.97 %
male: 27.03 %

What is the age of people who have Hypernatraemia when taking Lidocaine? *

What are other drugs people take besides Lidocaine? *

What are other side effects people have besides Hypernatraemia? *

Anaemia (lack of blood): 18 people, 48.65%
Infection: 15 people, 40.54%
Stomatitis (inflammation of mucous membrane of mouth): 12 people, 32.43%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 12 people, 32.43%
Fever: 12 people, 32.43%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 12 people, 32.43%
Wound Secretion: 11 people, 29.73%
Gums - Swollen: 11 people, 29.73%
Plasmacytoma (neoplasm of plasma cells (usually in bone marrow)): 11 people, 29.73%
Hair Loss: 11 people, 29.73%

What are the existing conditions these people have? *

Depression: 16 people, 43.24%
Insomnia (sleeplessness): 16 people, 43.24%
Nausea (feeling of having an urge to vomit): 16 people, 43.24%
Multiple Myeloma (cancer of the plasma cells): 11 people, 29.73%
Nausea And Vomiting: 11 people, 29.73%
Anaemia (lack of blood): 11 people, 29.73%
Stress And Anxiety: 6 people, 16.22%
Hypokalemia (low potassium): 6 people, 16.22%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 13.51%
Arrhythmias (irregular heartbeat): 5 people, 13.51%

* Approximation only. Some reports may have incomplete information.

Do you take Lidocaine and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lidocaine:

Lidocaine (27,555 reports)

Hypernatraemia treatments and more:

Hypernatraemia (6,339 reports)

Browse all side effects of Lidocaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Hypernatraemia (645 drugs)

Browse all the conditions that are associated with Hypernatraemia:

Hypernatraemia (807 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lidocaine (the active ingredients of Lidocaine) and Lidocaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.