Limbitrol and Rales - a phase IV clinical study of FDA data

Summary:

Rales is reported as a side effect among people who take Limbitrol (amitriptyline hydrochloride; chlordiazepoxide), especially for people who are female, 60+ old, also take Valium, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Rales when taking Limbitrol. It is created by eHealthMe based on reports of 361 people who have side effects when taking Limbitrol from the FDA, and is updated regularly.

What is Limbitrol?

Limbitrol has active ingredients of amitriptyline hydrochloride; chlordiazepoxide. It is often used in stress and anxiety. eHealthMe is studying from 378 Limbitrol users. Check the latest studies of Limbitrol.

What is Rales?

Rales (an abnormal respiratory sound characterized by fine crackles) is found to be associated with 904 drugs and 946 conditions by eHealthMe. Check the latest studies of Rales.

On Jul, 07, 2026

361 people reported to have side effects when taking Limbitrol.
Among them, 17 people (4.71%) have Rales.

Among these 17 people:

What is the gender of people who have Rales when taking Limbitrol? *

female: 94.12 %
male: 5.88 %

What is the age of people who have Rales when taking Limbitrol? *

What are other drugs people take besides Limbitrol? *

Lasix: 13 people, 76.47%
Valium: 13 people, 76.47%
Zyrtec: 12 people, 70.59%
Zoloft: 12 people, 70.59%
Cozaar: 12 people, 70.59%
Librax: 12 people, 70.59%
Flexeril: 12 people, 70.59%
Premarin: 12 people, 70.59%
Labetalol Hydrochloride: 11 people, 64.71%
Nexium: 11 people, 64.71%

What are other side effects people have besides Rales? *

Fever: 14 people, 82.35%
Infection: 13 people, 76.47%
Diarrhea: 13 people, 76.47%
Chest Pain: 13 people, 76.47%
Heart Attack: 13 people, 76.47%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 12 people, 70.59%
Fatigue (feeling of tiredness): 12 people, 70.59%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 12 people, 70.59%
Pleural Effusion (water on the lungs): 12 people, 70.59%
Pneumonia: 12 people, 70.59%

What are the existing conditions these people have? *

Pain In Jaw: 11 people, 64.71%
Multiple Myeloma (cancer of the plasma cells): 11 people, 64.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Osteoporosis (bones weak and more likely to break): 1 person, 5.88%
Neck Pain: 1 person, 5.88%
Iron Deficiency: 1 person, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.88%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 1 person, 5.88%
Back Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Limbitrol and have Rales?

- Check whether Rales is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Limbitrol:

Limbitrol (378 reports)

Rales treatments and more:

Rales (9,085 reports)

How severe was Rales and when was it recovered:

Rales in Limbitrol

Expand to all the drugs that have ingredients of amitriptyline hydrochloride; chlordiazepoxide:

Rales and drugs with ingredients of amitriptyline hydrochloride; chlordiazepoxide (17 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Limbitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rales:

Rales (904 drugs)

Browse all the conditions that are associated with Rales:

Rales (946 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride; chlordiazepoxide (the active ingredients of Limbitrol) and Limbitrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.