Lioresal and Spinal disorder - a phase IV clinical study of FDA data

Summary:

Spinal disorder is reported as a side effect among people who take Lioresal (baclofen), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Vancomycin, and have Muscle spasticity.

The phase IV clinical study analyzes which people have Spinal disorder when taking Lioresal. It is created by eHealthMe based on reports of 20,521 people who have side effects when taking Lioresal from the FDA, and is updated regularly.

What is Lioresal?

Lioresal has active ingredients of baclofen. It is often used in multiple sclerosis. eHealthMe is studying from 20,572 Lioresal users. Check the latest studies of Lioresal.

What is Spinal disorder?

Spinal disorder (disease of spine a back bone) is found to be associated with 905 drugs and 798 conditions by eHealthMe. Check the latest studies of Spinal disorder.



On Jul, 13, 2026

20,521 people reported to have side effects when taking Lioresal.
Among them, 17 people (0.08%) have Spinal disorder.

Could Lioresal cause Spinal disorder?

Among these 17 people:

How long have people been on Lioresal when they have Spinal disorder? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Spinal disorder when taking Lioresal? *

  • female: 41.18 %
  • male: 58.82 %

What is the age of people who have Spinal disorder when taking Lioresal? *

  • 0-1: 0.0 %
  • 2-9: 15.38 %
  • 10-19: 0.0 %
  • 20-29: 15.38 %
  • 30-39: 0.0 %
  • 40-49: 15.38 %
  • 50-59: 15.38 %
  • 60+: 38.46 %

What are other drugs people take besides Lioresal? *

  1. Vancomycin: 3 people, 17.65%
  2. Percocet: 2 people, 11.76%
  3. Levofloxacin: 2 people, 11.76%
  4. Lipitor: 2 people, 11.76%
  5. Flomax: 2 people, 11.76%
  6. Diflucan: 2 people, 11.76%
  7. Neurontin: 2 people, 11.76%
  8. Copaxone: 1 person, 5.88%
  9. Hydrocodone: 1 person, 5.88%
  10. Furosemide: 1 person, 5.88%

What are other side effects people have besides Spinal disorder? *

  1. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 29.41%
  2. Pain: 4 people, 23.53%
  3. Gait Disturbance: 3 people, 17.65%
  4. Nausea And Vomiting: 3 people, 17.65%
  5. Pain In Extremity: 2 people, 11.76%
  6. Fall: 2 people, 11.76%
  7. Dizziness: 2 people, 11.76%
  8. Device Dislocation: 2 people, 11.76%
  9. Joint Dislocation (a joint position is changed from normal position): 2 people, 11.76%
  10. Muscle Disorder (muscle disease): 2 people, 11.76%

What are the existing conditions these people have? *

  1. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 9 people, 52.94%
  2. Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 1 person, 5.88%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 5.88%
  4. Pain: 1 person, 5.88%
  5. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 5.88%
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 5.88%
  7. Diarrhea: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Lioresal and have Spinal disorder?

- Check whether Spinal disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lioresal:

Spinal disorder treatments and more:

How severe was Spinal disorder and when was it recovered:

Expand to all the drugs that have ingredients of baclofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lioresal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal disorder:

Browse all the conditions that are associated with Spinal disorder:


How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Lioresal) and Lioresal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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