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Lipitor and Claudication - a phase IV clinical study of FDA data

Summary:

Claudication is reported as a side effect among people who take Lipitor (atorvastatin calcium), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Plavix, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Claudication when taking Lipitor. It is created by eHealthMe based on reports of 251,142 people who have side effects when taking Lipitor from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,032 Lipitor users. Check the latest studies of Lipitor.

What is Claudication?

Claudication (muscle pain (ache, cramp, numbness or sense of fatigue)) is found to be associated with 1,154 drugs and 982 conditions by eHealthMe. Check the latest studies of Claudication.

On Oct, 08, 2025

251,142 people reported to have side effects when taking Lipitor.
Among them, 241 people (0.1%) have Claudication.

Could Lipitor cause Claudication?

Among these 241 people:

How long have people been on Lipitor when they have Claudication? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 30.77 %
  • 6 - 12 months: 15.38 %
  • 1 - 2 years: 7.69 %
  • 2 - 5 years: 30.77 %
  • 5 - 10 years: 15.38 %
  • 10+ years: 0.0 %

What is the gender of people who have Claudication when taking Lipitor? *

  • female: 32.07 %
  • male: 67.93 %

What is the age of people who have Claudication when taking Lipitor? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.55 %
  • 30-39: 1.1 %
  • 40-49: 4.97 %
  • 50-59: 24.31 %
  • 60+: 69.06 %

What are other drugs people take besides Lipitor? *

  1. Plavix: 82 people, 34.02%
  2. Aspirin: 71 people, 29.46%
  3. Prilosec: 67 people, 27.80%
  4. Lasix: 61 people, 25.31%
  5. Lisinopril: 60 people, 24.90%
  6. Digoxin: 57 people, 23.65%
  7. Zometa: 56 people, 23.24%
  8. Vioxx: 51 people, 21.16%
  9. Toprol-Xl: 50 people, 20.75%
  10. Protonix: 47 people, 19.50%

What are other side effects people have besides Claudication? *

  1. Chest Pain: 88 people, 36.51%
  2. Stress And Anxiety: 70 people, 29.05%
  3. Joint Pain: 70 people, 29.05%
  4. Dyspnea (difficult or laboured breathing): 68 people, 28.22%
  5. Pain: 66 people, 27.39%
  6. Dizziness: 62 people, 25.73%
  7. Fatigue (feeling of tiredness): 62 people, 25.73%
  8. Back Pain: 61 people, 25.31%
  9. Nausea (feeling of having an urge to vomit): 61 people, 25.31%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 60 people, 24.90%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 34 people, 14.11%
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 6.64%
  3. Bone Disorder: 15 people, 6.22%
  4. Type 2 Diabetes: 12 people, 4.98%
  5. Pain: 10 people, 4.15%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 4.15%
  7. Hyperlipidaemia (presence of excess lipids in the blood): 10 people, 4.15%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 3.32%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 3.32%
  10. Nausea (feeling of having an urge to vomit): 8 people, 3.32%

* Approximation only. Some reports may have incomplete information.

Do you take Lipitor and have Claudication?

- Check whether Claudication is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lipitor:

Claudication treatments and more:

How severe was Claudication and when was it recovered:

Expand to all the drugs that have ingredients of atorvastatin calcium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Lipitor side effects:

Browse all side effects of Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Claudication:

Browse all the drugs that are associated with Claudication:

Common conditions associated with Claudication:

Browse all the conditions that are associated with Claudication:

Drugs similar to Lipitor and Claudication :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on atorvastatin calcium (the active ingredients of Lipitor) and Lipitor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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