Lipitor and Hyperprolactinaemia - a phase IV clinical study of FDA data

Summary:

Hyperprolactinaemia is reported as a side effect among people who take Lipitor (atorvastatin calcium), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Seroquel, and have Depression.

The phase IV clinical study analyzes which people have Hyperprolactinaemia when taking Lipitor. It is created by eHealthMe based on reports of 251,142 people who have side effects when taking Lipitor from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.

What is Hyperprolactinaemia?

Hyperprolactinaemia (abnormally high levels of prolactin in the blood) is found to be associated with 213 drugs and 392 conditions by eHealthMe. Check the latest studies of Hyperprolactinaemia.



On Jul, 26, 2026

251,142 people reported to have side effects when taking Lipitor.
Among them, 15 people (0.01%) have Hyperprolactinaemia.

Could Lipitor cause Hyperprolactinaemia?

Among these 15 people:

How long have people been on Lipitor when they have Hyperprolactinaemia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the gender of people who have Hyperprolactinaemia when taking Lipitor? *

  • female: 53.33 %
  • male: 46.67 %

What is the age of people who have Hyperprolactinaemia when taking Lipitor? *

  • 0-1: 8.33 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 8.33 %
  • 40-49: 33.33 %
  • 50-59: 25.0 %
  • 60+: 25.0 %

What are other drugs people take besides Lipitor? *

  1. Neurontin: 7 people, 46.67%
  2. Seroquel: 7 people, 46.67%
  3. Synthroid: 5 people, 33.33%
  4. Lexapro: 4 people, 26.67%
  5. Diazepam: 4 people, 26.67%
  6. Tricor: 4 people, 26.67%
  7. Lorazepam: 4 people, 26.67%
  8. Risperdal: 4 people, 26.67%
  9. Depakote: 4 people, 26.67%
  10. Bextra: 4 people, 26.67%

What are other side effects people have besides Hyperprolactinaemia? *

  1. Type 2 Diabetes: 5 people, 33.33%
  2. Back Pain: 5 people, 33.33%
  3. Cardiac Disorder: 4 people, 26.67%
  4. Headache (pain in head): 4 people, 26.67%
  5. Heart Attack: 4 people, 26.67%
  6. Arrhythmias (irregular heartbeat): 3 people, 20.00%
  7. Depression: 3 people, 20.00%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 20.00%
  9. Fatigue (feeling of tiredness): 3 people, 20.00%
  10. Hyperthyroidism (over activity of the thyroid gland): 3 people, 20.00%

What are the existing conditions these people have? *

  1. Bipolar Disorder (mood disorder): 4 people, 26.67%
  2. Depression: 4 people, 26.67%
  3. Mood Swings (an extreme or rapid change in mood): 3 people, 20.00%
  4. Sleep Disorder: 3 people, 20.00%
  5. Stress And Anxiety: 1 person, 6.67%
  6. Headache (pain in head): 1 person, 6.67%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.67%
  8. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 6.67%
  9. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 6.67%
  10. Diabetes: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lipitor and have Hyperprolactinaemia?

- Check whether Hyperprolactinaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lipitor:

Hyperprolactinaemia treatments and more:

How severe was Hyperprolactinaemia and when was it recovered:

Expand to all the drugs that have ingredients of atorvastatin calcium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperprolactinaemia:

Browse all the conditions that are associated with Hyperprolactinaemia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on atorvastatin calcium (the active ingredients of Lipitor) and Lipitor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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