Lipitor and Rheumatoid nodule - a phase IV clinical study of FDA data

Summary:

Rheumatoid nodule is reported as a side effect among people who take Lipitor (atorvastatin calcium), especially for people who are female, 60+ old, also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Rheumatoid nodule when taking Lipitor. It is created by eHealthMe based on reports of 251,142 people who have side effects when taking Lipitor from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.

What is Rheumatoid nodule?

Rheumatoid nodule (a local swelling or tissue lump with rheumatoid disease) is found to be associated with 252 drugs and 226 conditions by eHealthMe. Check the latest studies of Rheumatoid nodule.



On Jul, 05, 2026

251,142 people reported to have side effects when taking Lipitor.
Among them, 39 people (0.02%) have Rheumatoid nodule.

Could Lipitor cause Rheumatoid nodule?

Among these 39 people:

What is the gender of people who have Rheumatoid nodule when taking Lipitor? *

  • female: 79.49 %
  • male: 20.51 %

What is the age of people who have Rheumatoid nodule when taking Lipitor? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 40 %
  • 50-59: 4 %
  • 60+: 56 %

What are other drugs people take besides Lipitor? *

  1. Humira: 19 people, 48.72%
  2. Enbrel: 16 people, 41.03%
  3. Methotrexate: 16 people, 41.03%
  4. Folic Acid: 15 people, 38.46%
  5. Arava: 11 people, 28.21%
  6. Remicade: 9 people, 23.08%
  7. Plaquenil: 8 people, 20.51%
  8. Celebrex: 8 people, 20.51%
  9. Prednisone: 8 people, 20.51%
  10. Synthroid: 7 people, 17.95%

What are other side effects people have besides Rheumatoid nodule? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 43.59%
  2. Pain In Extremity: 16 people, 41.03%
  3. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 15 people, 38.46%
  4. Peripheral Swelling: 15 people, 38.46%
  5. Joint Pain: 15 people, 38.46%
  6. Fatigue (feeling of tiredness): 15 people, 38.46%
  7. Drug Ineffective: 14 people, 35.90%
  8. Dizziness: 13 people, 33.33%
  9. Nausea (feeling of having an urge to vomit): 12 people, 30.77%
  10. Diarrhea: 11 people, 28.21%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 36 people, 92.31%
  2. Pain: 5 people, 12.82%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 12.82%
  4. Back Pain: 5 people, 12.82%
  5. Inflammation: 4 people, 10.26%
  6. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 4 people, 10.26%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.69%
  8. Sleep Disorder: 2 people, 5.13%
  9. Cardiac Disorder: 2 people, 5.13%
  10. Diabetes: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Lipitor and have Rheumatoid nodule?

- Check whether Rheumatoid nodule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lipitor:

Rheumatoid nodule treatments and more:

How severe was Rheumatoid nodule and when was it recovered:

Expand to all the drugs that have ingredients of atorvastatin calcium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lipitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rheumatoid nodule:

Browse all the conditions that are associated with Rheumatoid nodule:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on atorvastatin calcium (the active ingredients of Lipitor) and Lipitor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: