Lipoic acid and Umbilical hernia - a phase IV clinical study of FDA data

Summary:

Umbilical hernia is reported as a side effect among people who take Lipoic acid (alpha - lipoic acid), especially for people who are male, 60+ old, also take Thalidomide, and have High blood pressure.

The phase IV clinical study analyzes which people have Umbilical hernia when taking Lipoic acid. It is created by eHealthMe based on reports of 5,562 people who have side effects when taking Lipoic acid from the FDA, and is updated regularly.

What is Lipoic acid?

Lipoic acid has active ingredients of alpha - lipoic acid. It is often used in peripheral neuropathy. eHealthMe is studying from 5,920 Lipoic acid users. Check the latest studies of Lipoic acid.

What is Umbilical hernia?

Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button) is found to be associated with 644 drugs and 676 conditions by eHealthMe. Check the latest studies of Umbilical hernia.

On Aug, 09, 2026

5,562 people reported to have side effects when taking Lipoic acid.
Among them, 24 people (0.43%) have Umbilical hernia.

Could Lipoic acid cause Umbilical hernia?

Among these 24 people:

What is the gender of people who have Umbilical hernia when taking Lipoic acid? *

female: 0.0 %
male: 100 %

What is the age of people who have Umbilical hernia when taking Lipoic acid? *

What are other drugs people take besides Lipoic acid? *

What are other side effects people have besides Umbilical hernia? *

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 24 people, 100.00%
Bone Disorder: 24 people, 100.00%
Gingival Pain (gum pain): 24 people, 100.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 24 people, 100.00%
Fainting (loss of consciousness and postural tone): 24 people, 100.00%
Joint Pain: 24 people, 100.00%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 24 people, 100.00%
Multiple Myeloma (cancer of the plasma cells): 24 people, 100.00%
Oral Pain: 24 people, 100.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 24 people, 100.00%

What are the existing conditions these people have? *

High Blood Pressure: 24 people, 100.00%
Joint Pain: 23 people, 95.83%
Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 23 people, 95.83%
Diarrhea: 23 people, 95.83%
Fluid Retention (an abnormal accumulation of fluid in the blood): 23 people, 95.83%
High Blood Cholesterol: 23 people, 95.83%
Multiple Myeloma (cancer of the plasma cells): 23 people, 95.83%
Mood Swings (an extreme or rapid change in mood): 23 people, 95.83%
Blood Triglycerides Decreased: 18 people, 75.00%
Seasonal Allergy (allergic condition due to certain season): 18 people, 75.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lipoic acid and have Umbilical hernia?

- Check whether Umbilical hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lipoic acid:

Lipoic acid (5,920 reports)

Browse all side effects of Lipoic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Umbilical hernia:

Umbilical hernia (644 drugs)

Browse all the conditions that are associated with Umbilical hernia:

Umbilical hernia (676 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alpha - lipoic acid (the active ingredients of Lipoic acid) and Lipoic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.