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Lisinopril and Gingival hyperplasia - a phase IV clinical study of FDA data

Summary:

Gingival hyperplasia is reported as a side effect among people who take Lisinopril (lisinopril), especially for people who are male, 50-59 old, also take Lipitor, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Gingival hyperplasia when taking Lisinopril. It is created by eHealthMe based on reports of 343,814 people who have side effects when taking Lisinopril from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,657 Lisinopril users. Check the latest studies of Lisinopril.

What is Gingival hyperplasia?

Gingival hyperplasia (overgrowth of gums) is found to be associated with 154 drugs and 263 conditions by eHealthMe. Check the latest studies of Gingival hyperplasia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

343,814 people reported to have side effects when taking Lisinopril.
Among them, 24 people (0.01%) have Gingival hyperplasia.

Could Lisinopril cause Gingival hyperplasia?

Among these 24 people:

What is the gender of people who have Gingival hyperplasia when taking Lisinopril? *

  • female: 45.83 %
  • male: 54.17 %

What is the age of people who have Gingival hyperplasia when taking Lisinopril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 50.0 %
  • 60+: 22.22 %

What are other drugs people take besides Lisinopril? *

  1. Lipitor: 9 people, 37.50%
  2. Aciphex: 7 people, 29.17%
  3. Synthroid: 7 people, 29.17%
  4. Digoxin: 7 people, 29.17%
  5. Herceptin: 7 people, 29.17%
  6. Demerol: 7 people, 29.17%
  7. Dalmane: 7 people, 29.17%
  8. Mevacor: 7 people, 29.17%
  9. Zometa: 7 people, 29.17%
  10. Coumadin: 7 people, 29.17%

What are other side effects people have besides Gingival hyperplasia? *

  1. Gingival Bleeding (bleeding gums): 11 people, 45.83%
  2. Gingival Pain (gum pain): 11 people, 45.83%
  3. Gingivitis (inflammation of gums): 9 people, 37.50%
  4. Rashes (redness): 8 people, 33.33%
  5. Dizziness: 8 people, 33.33%
  6. Impaired Healing: 7 people, 29.17%
  7. Pain: 7 people, 29.17%
  8. Oral Discomfort (pain or irritation in mouth): 7 people, 29.17%
  9. Muscle Spasms (muscle contraction): 7 people, 29.17%
  10. Metastases To Lung (cancer spreads to lung): 7 people, 29.17%

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 8 people, 33.33%
  2. Breast Cancer Metastatic: 7 people, 29.17%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 29.17%
  4. Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 3 people, 12.50%
  5. Dyslipidaemia (abnormal amount of lipids): 3 people, 12.50%
  6. Focal Glomerulosclerosis (disease that attacks the kidney's filtering system (glomeruli) causing serious scarring): 2 people, 8.33%
  7. Bipolar Disorder (mood disorder): 2 people, 8.33%
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 8.33%
  9. Thyroid Diseases: 1 person, 4.17%
  10. Back Pain: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and have Gingival hyperplasia?

- Check whether Gingival hyperplasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lisinopril:

Gingival hyperplasia treatments and more:

How severe was Gingival hyperplasia and when was it recovered:

Expand to all the drugs that have ingredients of lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gingival hyperplasia:

Browse all the conditions that are associated with Gingival hyperplasia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Lisinopril) and Lisinopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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