Lisinopril and Hyperlactacidaemia - a phase IV clinical study of FDA data

Summary:

Hyperlactacidaemia is reported as a side effect among people who take Lisinopril (lisinopril), especially for people who are male, 60+ old, also take Metformin, and have Hiv infection.

The phase IV clinical study analyzes which people have Hyperlactacidaemia when taking Lisinopril. It is created by eHealthMe based on reports of 343,814 people who have side effects when taking Lisinopril from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,608 Lisinopril users. Check the latest studies of Lisinopril.

What is Hyperlactacidaemia?

Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney) is found to be associated with 274 drugs and 264 conditions by eHealthMe. Check the latest studies of Hyperlactacidaemia.

On Oct, 11, 2025

343,814 people reported to have side effects when taking Lisinopril.
Among them, 28 people (0.01%) have Hyperlactacidaemia.

Could Lisinopril cause Hyperlactacidaemia?

Among these 28 people:

What is the gender of people who have Hyperlactacidaemia when taking Lisinopril? *

female: 20.83 %
male: 79.17 %

What is the age of people who have Hyperlactacidaemia when taking Lisinopril? *

What are other drugs people take besides Lisinopril? *

Metformin: 14 people, 50.00%
Aspirin: 11 people, 39.29%
Empagliflozin: 11 people, 39.29%
Levetiracetam: 6 people, 21.43%
Isosorbide Mononitrate: 6 people, 21.43%
Raltegravir: 6 people, 21.43%
Potassium Gluconate: 6 people, 21.43%
Omeprazole: 6 people, 21.43%
Lovastatin: 6 people, 21.43%
Novolog: 5 people, 17.86%

What are other side effects people have besides Hyperlactacidaemia? *

Nausea And Vomiting: 19 people, 67.86%
Malaise (a feeling of general discomfort or uneasiness): 12 people, 42.86%
Acidosis (build-up of carbon dioxide in the blood): 12 people, 42.86%
Hyperglycemia (high blood sugar): 12 people, 42.86%
Cardiac Arrest: 12 people, 42.86%
Fatigue (feeling of tiredness): 6 people, 21.43%
Mitochondrial Toxicity (a condition in which the mitochondria of a body's cells become damaged or decline significantly in number;): 6 people, 21.43%
Lactic Acidosis (low ph in body tissues): 6 people, 21.43%
Aspartate Aminotransferase Increased: 5 people, 17.86%
Gamma-Glutamyltransferase Increased: 5 people, 17.86%

What are the existing conditions these people have? *

Hiv Infection: 11 people, 39.29%
Type 2 Diabetes: 2 people, 7.14%
Gout (uric acid crystals building up in the body): 2 people, 7.14%
Diabetes: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and have Hyperlactacidaemia?

- Check whether Hyperlactacidaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lisinopril:

Lisinopril (358,608 reports)

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperlactacidaemia:

Hyperlactacidaemia (274 drugs)

Browse all the conditions that are associated with Hyperlactacidaemia:

Hyperlactacidaemia (264 conditions)

Drugs similar to Lisinopril and Hyperlactacidaemia :

Related publications that referenced our studies

Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Lisinopril) and Lisinopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.