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Lisinopril and Hyperpyrexia - a phase IV clinical study of FDA data

Summary:

Hyperpyrexia is reported as a side effect among people who take Lisinopril (lisinopril), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Diabetes.

The phase IV clinical study analyzes which people have Hyperpyrexia when taking Lisinopril. It is created by eHealthMe based on reports of 343,814 people who have side effects when taking Lisinopril from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,650 Lisinopril users. Check the latest studies of Lisinopril.

What is Hyperpyrexia?

Hyperpyrexia (extremely high fever) is found to be associated with 385 drugs and 528 conditions by eHealthMe. Check the latest studies of Hyperpyrexia.

On Jun, 13, 2026

343,814 people reported to have side effects when taking Lisinopril.
Among them, 22 people (0.01%) have Hyperpyrexia.

Could Lisinopril cause Hyperpyrexia?

Among these 22 people:

How long have people been on Lisinopril when they have Hyperpyrexia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperpyrexia when taking Lisinopril? *

  • female: 40.91 %
  • male: 59.09 %

What is the age of people who have Hyperpyrexia when taking Lisinopril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.26 %
  • 50-59: 0.0 %
  • 60+: 94.74 %

What are other drugs people take besides Lisinopril? *

  1. Insulin: 4 people, 18.18%
  2. Magnesium: 4 people, 18.18%
  3. Vancomycin: 4 people, 18.18%
  4. Ibrutinib: 4 people, 18.18%
  5. Metformin: 4 people, 18.18%
  6. Digoxin: 3 people, 13.64%
  7. Simvastatin: 2 people, 9.09%
  8. Flomax: 2 people, 9.09%
  9. Proscar: 2 people, 9.09%
  10. Phenazopyridine Hcl Tab: 2 people, 9.09%

What are other side effects people have besides Hyperpyrexia? *

  1. Arrhythmias (irregular heartbeat): 11 people, 50.00%
  2. Fatigue (feeling of tiredness): 10 people, 45.45%
  3. Nausea (feeling of having an urge to vomit): 5 people, 22.73%
  4. Neuropathy Peripheral (surface nerve damage): 5 people, 22.73%
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 22.73%
  6. Malaise (a feeling of general discomfort or uneasiness): 5 people, 22.73%
  7. Hypotension (abnormally low blood pressure): 5 people, 22.73%
  8. Erythema Multiforme (a type of hypersensitivity reaction): 5 people, 22.73%
  9. Tachypnea: 5 people, 22.73%
  10. Lower Respiratory Tract Infection: 4 people, 18.18%

What are the existing conditions these people have? *

  1. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 4 people, 18.18%
  2. Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 18.18%
  3. Diabetes: 4 people, 18.18%
  4. Bladder Cancer: 2 people, 9.09%
  5. High Blood Cholesterol: 2 people, 9.09%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 4.55%
  7. Back Pain: 1 person, 4.55%
  8. Blood Glucose Fluctuation: 1 person, 4.55%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.55%
  10. Hypoaesthesia (reduced sense of touch or sensation): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and have Hyperpyrexia?

- Check whether Hyperpyrexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lisinopril:

Hyperpyrexia treatments and more:

How severe was Hyperpyrexia and when was it recovered:

Expand to all the drugs that have ingredients of lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperpyrexia:

Browse all the conditions that are associated with Hyperpyrexia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Lisinopril) and Lisinopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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