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Lisinopril and Hypertensive nephropathy - a phase IV clinical study of FDA data

Summary:

Hypertensive nephropathy is reported as a side effect among people who take Lisinopril (lisinopril), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Hypertensive nephropathy when taking Lisinopril. It is created by eHealthMe based on reports of 343,814 people who have side effects when taking Lisinopril from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,656 Lisinopril users. Check the latest studies of Lisinopril.

What is Hypertensive nephropathy?

Hypertensive nephropathy (hypertensive renal disease) is found to be associated with 160 drugs and 206 conditions by eHealthMe. Check the latest studies of Hypertensive nephropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

343,814 people reported to have side effects when taking Lisinopril.
Among them, 59 people (0.02%) have Hypertensive nephropathy.

Could Lisinopril cause Hypertensive nephropathy?

Among these 59 people:

How long have people been on Lisinopril when they have Hypertensive nephropathy? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 42.86 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 42.86 %
  • 5 - 10 years: 14.29 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypertensive nephropathy when taking Lisinopril? *

  • female: 51.79 %
  • male: 48.21 %

What is the age of people who have Hypertensive nephropathy when taking Lisinopril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.26 %
  • 20-29: 0.0 %
  • 30-39: 8.51 %
  • 40-49: 8.51 %
  • 50-59: 29.79 %
  • 60+: 48.94 %

What are other drugs people take besides Lisinopril? *

  1. Nexium: 17 people, 28.81%
  2. Prilosec: 16 people, 27.12%
  3. Lipitor: 14 people, 23.73%
  4. Prevacid: 13 people, 22.03%
  5. Nexium 24hr: 10 people, 16.95%
  6. Aspirin: 9 people, 15.25%
  7. Lyrica: 9 people, 15.25%
  8. Furosemide: 8 people, 13.56%
  9. Lasix: 8 people, 13.56%
  10. Prevacid 24 Hr: 8 people, 13.56%

What are other side effects people have besides Hypertensive nephropathy? *

  1. Chronic Kidney Disease: 26 people, 44.07%
  2. Acute Kidney Failure: 20 people, 33.90%
  3. Chronic Renal Failure (kidney failure): 13 people, 22.03%
  4. Constipation: 12 people, 20.34%
  5. Nausea (feeling of having an urge to vomit): 12 people, 20.34%
  6. Chest Pain: 12 people, 20.34%
  7. Pain: 10 people, 16.95%
  8. Fatigue (feeling of tiredness): 9 people, 15.25%
  9. Hypotension (abnormally low blood pressure): 9 people, 15.25%
  10. Diabetic Nephropathy (diabetic kidney disease): 9 people, 15.25%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 18.64%
  2. Pain: 6 people, 10.17%
  3. Osteoporosis (bones weak and more likely to break): 6 people, 10.17%
  4. Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 10.17%
  5. Type 2 Diabetes: 5 people, 8.47%
  6. Diabetes: 5 people, 8.47%
  7. Depression: 4 people, 6.78%
  8. High Blood Cholesterol: 4 people, 6.78%
  9. Indigestion: 4 people, 6.78%
  10. Limb Discomfort (discomfort in leg): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and have Hypertensive nephropathy?

- Check whether Hypertensive nephropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lisinopril:

Hypertensive nephropathy treatments and more:

How severe was Hypertensive nephropathy and when was it recovered:

Expand to all the drugs that have ingredients of lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertensive nephropathy:

Browse all the conditions that are associated with Hypertensive nephropathy:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Lisinopril) and Lisinopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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