Lisinopril and Joint instability - a phase IV clinical study of FDA data

Summary:

Joint instability is reported as a side effect among people who take Lisinopril (lisinopril), especially for people who are female, 60+ old, also take Humira, and have Diabetes.

The phase IV clinical study analyzes which people have Joint instability when taking Lisinopril. It is created by eHealthMe based on reports of 343,814 people who have side effects when taking Lisinopril from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,657 Lisinopril users. Check the latest studies of Lisinopril.

What is Joint instability?

Joint instability (a condition in which the joints aren't sufficiently supported) is found to be associated with 230 drugs and 371 conditions by eHealthMe. Check the latest studies of Joint instability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

343,814 people reported to have side effects when taking Lisinopril.
Among them, 60 people (0.02%) have Joint instability.

Could Lisinopril cause Joint instability?

Among these 60 people:

What is the gender of people who have Joint instability when taking Lisinopril? *

female: 61.4 %
male: 38.6 %

What is the age of people who have Joint instability when taking Lisinopril? *

What are other drugs people take besides Lisinopril? *

What are other side effects people have besides Joint instability? *

Joint Pain: 31 people, 51.67%
Fall: 21 people, 35.00%
Weakness: 21 people, 35.00%
Pain In Extremity: 19 people, 31.67%
Pain: 14 people, 23.33%
Back Pain: 13 people, 21.67%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 11 people, 18.33%
Joint Swelling: 11 people, 18.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 16.67%
Fatigue (feeling of tiredness): 9 people, 15.00%

What are the existing conditions these people have? *

Diabetes: 12 people, 20.00%
High Blood Cholesterol: 10 people, 16.67%
Psoriasis (immune-mediated disease that affects the skin): 10 people, 16.67%
Cardiac Disorder: 10 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 16.67%
Pain: 8 people, 13.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 11.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 8.33%
Depression: 5 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and have Joint instability?

- Check whether Joint instability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lisinopril:

Lisinopril (358,657 reports)

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint instability:

Joint instability (230 drugs)

Browse all the conditions that are associated with Joint instability:

Joint instability (371 conditions)

Related publications that referenced our studies

Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Lisinopril) and Lisinopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.