Listerine and Dyspnea - a phase IV clinical study of FDA data

Summary:

Dyspnea is reported as a side effect among people who take Listerine (menthol, thymol, methyl salicylate, eucalyptol), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Metoclopramide, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Dyspnea when taking Listerine. It is created by eHealthMe based on reports of 1,150 people who have side effects when taking Listerine from the FDA, and is updated regularly.

What is Listerine?

Listerine has active ingredients of menthol, thymol, methyl salicylate, eucalyptol. eHealthMe is studying from 1,164 Listerine users. Check the latest studies of Listerine.

What is Dyspnea?

Dyspnea (difficult or laboured breathing) is found to be associated with 3,725 drugs and 6,067 conditions by eHealthMe. Check the latest studies of Dyspnea.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

1,150 people reported to have side effects when taking Listerine.
Among them, 31 people (2.7%) have Dyspnea.

Among these 31 people:

How long have people been on Listerine when they have Dyspnea? *

What is the gender of people who have Dyspnea when taking Listerine? *

female: 72.41 %
male: 27.59 %

What is the age of people who have Dyspnea when taking Listerine? *

What are other drugs people take besides Listerine? *

What are other side effects people have besides Dyspnea? *

Balance Disorder: 8 people, 25.81%
Weakness: 8 people, 25.81%
Hoarseness Or Changing Voice: 8 people, 25.81%
Oral Candidiasis (fungal infection of mouth): 7 people, 22.58%
Lower Respiratory Tract Infection: 6 people, 19.35%
Stomatitis (inflammation of mucous membrane of mouth): 6 people, 19.35%
Oral Pain: 6 people, 19.35%
Pneumonia: 6 people, 19.35%
Poor Quality Sleep: 6 people, 19.35%
Postoperative Wound Complication: 6 people, 19.35%

What are the existing conditions these people have? *

Gastrointestinal Hypomotility (less activity of the intestinal tract): 6 people, 19.35%
Osteoporosis (bones weak and more likely to break): 6 people, 19.35%
Bone Pain: 6 people, 19.35%
Breast Cancer: 6 people, 19.35%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 19.35%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.68%
Asthma: 3 people, 9.68%
Faeces Hard: 2 people, 6.45%
Hypersensitivity: 2 people, 6.45%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Listerine and have Dyspnea?

- Check whether Dyspnea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Listerine:

Listerine (1,164 reports)

Dyspnea treatments and more:

Dyspnea (661,578 reports)

How severe was Dyspnea and when was it recovered:

Dyspnea in Listerine

Expand to all the drugs that have ingredients of menthol, thymol, methyl salicylate, eucalyptol:

Dyspnea and drugs with ingredients of menthol, thymol, methyl salicylate, eucalyptol (35 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Listerine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dyspnea:

Dyspnea (3,725 drugs)

Browse all the conditions that are associated with Dyspnea:

Dyspnea (6,067 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on menthol, thymol, methyl salicylate, eucalyptol (the active ingredients of Listerine) and Listerine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.