Locoid and Ascites - a phase IV clinical study of FDA data

Summary:

Ascites is reported as a side effect among people who take Locoid (hydrocortisone butyrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have High blood pressure.

The phase IV clinical study analyzes which people have Ascites when taking Locoid. It is created by eHealthMe based on reports of 1,990 people who have side effects when taking Locoid from the FDA, and is updated regularly.

What is Locoid?

Locoid has active ingredients of hydrocortisone butyrate. eHealthMe is studying from 1,996 Locoid users. Check the latest studies of Locoid.

What is Ascites?

Ascites (accumulation of fluid in the abdominal cavity) is found to be associated with 1,532 drugs and 2,031 conditions by eHealthMe. Check the latest studies of Ascites.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

1,990 people reported to have side effects when taking Locoid.
Among them, 20 people (1.01%) have Ascites.

Among these 20 people:

How long have people been on Locoid when they have Ascites? *

What is the gender of people who have Ascites when taking Locoid? *

female: 63.16 %
male: 36.84 %

What is the age of people who have Ascites when taking Locoid? *

What are other drugs people take besides Locoid? *

What are other side effects people have besides Ascites? *

Anaemia (lack of blood): 11 people, 55.00%
Fever: 8 people, 40.00%
Thrombocytopenia (decrease of platelets in blood): 8 people, 40.00%
Liver Disorder (liver diseases): 6 people, 30.00%
Hepatitis C: 5 people, 25.00%
Histiocytosis Haematophagic: 5 people, 25.00%
Oedema (fluid collection in tissue): 5 people, 25.00%
Multi-Organ Failure (multisystem organ failure): 5 people, 25.00%
Itching: 5 people, 25.00%
Renal Disorder (kidney disease): 5 people, 25.00%

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 50.00%
Insomnia (sleeplessness): 7 people, 35.00%
Hepatitis C: 5 people, 25.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 25.00%
Hepatic Neoplasm Malignant (liver cancer): 4 people, 20.00%
Hepatic Function Abnormal: 4 people, 20.00%
Gastritis (inflammation of stomach): 4 people, 20.00%
Pain: 4 people, 20.00%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 15.00%
Erythema Multiforme (a type of hypersensitivity reaction): 3 people, 15.00%

* Approximation only. Some reports may have incomplete information.

Do you take Locoid and have Ascites?

- Check whether Ascites is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Locoid:

Locoid (1,996 reports)

Ascites treatments and more:

Ascites (42,930 reports)

Browse all side effects of Locoid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ascites:

Ascites (1,532 drugs)

Browse all the conditions that are associated with Ascites:

Ascites (2,031 conditions)

Related publications that referenced our studies

Rajsekhar P, Reddy MM, Vaddera S, Rajini G, Tikeli V, "A Rare Case of Vitamin B12 Deficiency with Ascites", Journal of clinical and diagnostic research: JCDR, 2014 Jan .
Rajsekhar P, Reddy MM, Vaddera S, Rajini G, Tikeli V, "A Rare Case of Vitamin B12 Deficiency with Ascites", Journal of clinical and diagnostic research: JCDR, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone butyrate (the active ingredients of Locoid) and Locoid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.