Lopurin and Hoarseness - a phase IV clinical study of FDA data

Summary:

Hoarseness is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 50-59 old, also take Spironolactone, and have Asthma.

The phase IV clinical study analyzes which people have Hoarseness when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.

What is Hoarseness?

Hoarseness (changing voice) is found to be associated with 210 drugs and 347 conditions by eHealthMe. Check the latest studies of Hoarseness.

On Jul, 12, 2026

188,140 people reported to have side effects when taking Lopurin.
Among them, 16 people (0.01%) have Hoarseness.

Among these 16 people:

What is the gender of people who have Hoarseness when taking Lopurin? *

female: 18.75 %
male: 81.25 %

What is the age of people who have Hoarseness when taking Lopurin? *

What are other drugs people take besides Lopurin? *

Theophylline: 4 people, 25.00%
Spironolactone: 4 people, 25.00%
Singulair: 3 people, 18.75%
Furosemide: 3 people, 18.75%
Fenoterol Hydrobromide: 3 people, 18.75%
Dipyrone: 3 people, 18.75%
Accutane: 2 people, 12.50%
Isosorbide Mononitrate: 2 people, 12.50%
Famvir: 2 people, 12.50%
Paxil: 2 people, 12.50%

What are other side effects people have besides Hoarseness? *

Oedema Lower Limb (fluid collection in tissue of lower leg): 4 people, 25.00%
Itching: 4 people, 25.00%
Joint Pain: 3 people, 18.75%
Bleeding Into The Skin: 3 people, 18.75%
Telangiectasia (small dilated blood vessels near the surface of the skin): 3 people, 18.75%
Fatty Liver: 3 people, 18.75%
Feeling Hot: 3 people, 18.75%
Gallstones (stone formation by bile component): 3 people, 18.75%
Haematuria Present (presence of blood in urine due to trauma): 3 people, 18.75%
Laryngeal Nerve Damage: 3 people, 18.75%

What are the existing conditions these people have? *

Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 6.25%
Oesophageal Candidiasis (fungal infection of oesophagus): 1 person, 6.25%
High Blood Cholesterol: 1 person, 6.25%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%
Asthma: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Hoarseness?

- Check whether Hoarseness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,798 reports)

Hoarseness treatments and more:

Hoarseness (2,548 reports)

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hoarseness:

Hoarseness (210 drugs)

Browse all the conditions that are associated with Hoarseness:

Hoarseness (347 conditions)

Related publications that referenced our studies

Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.