Lopurin and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Lopurin (allopurinol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Lopurin. It is created by eHealthMe based on reports of 188,140 people who have side effects when taking Lopurin from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,785 Lopurin users. Check the latest studies of Lopurin.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,187 drugs and 840 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Dec, 11, 2025

188,140 people reported to have side effects when taking Lopurin.
Among them, 138 people (0.07%) have Sinus node dysfunction.

Could Lopurin cause Sinus node dysfunction?

Among these 138 people:

How long have people been on Lopurin when they have Sinus node dysfunction? *

Click here to view more results

What is the gender of people who have Sinus node dysfunction when taking Lopurin? *

Click here to view

What is the age of people who have Sinus node dysfunction when taking Lopurin? *

Click here to view more results

* Approximation only. Some reports may have incomplete information.

Do you take Lopurin and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lopurin:

Lopurin (190,785 reports)

Sinus node dysfunction treatments and more:

Sinus node dysfunction (4,617 reports)

How severe was Sinus node dysfunction and when was it recovered:

Sinus node dysfunction in Lopurin

Expand to all the drugs that have ingredients of allopurinol:

Sinus node dysfunction and drugs with ingredients of allopurinol (137 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Lopurin side effects:

Browse all side effects of Lopurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sinus node dysfunction:

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,187 drugs)

Common conditions associated with Sinus node dysfunction:

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (840 conditions)

Drugs similar to Lopurin and Sinus node dysfunction :

Indomethacin side effect: Sinus node dysfunction

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Lopurin) and Lopurin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.