Lorazepam and Coma hepatic - a phase IV clinical study of FDA data

Summary:

Coma hepatic is reported as a side effect among people who take Lorazepam (lorazepam), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Creon, and have Lipids increased.

The phase IV clinical study analyzes which people have Coma hepatic when taking Lorazepam. It is created by eHealthMe based on reports of 161,687 people who have side effects when taking Lorazepam from the FDA, and is updated regularly.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

What is Coma hepatic?

Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma) is found to be associated with 149 drugs and 409 conditions by eHealthMe. Check the latest studies of Coma hepatic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

161,687 people reported to have side effects when taking Lorazepam.
Among them, 28 people (0.02%) have Coma hepatic.

Among these 28 people:

How long have people been on Lorazepam when they have Coma hepatic? *

What is the gender of people who have Coma hepatic when taking Lorazepam? *

female: 74.07 %
male: 25.93 %

What is the age of people who have Coma hepatic when taking Lorazepam? *

What are other drugs people take besides Lorazepam? *

What are other side effects people have besides Coma hepatic? *

Acute Hepatic Failure: 12 people, 42.86%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 12 people, 42.86%
Autoimmune Hepatitis: 9 people, 32.14%
Agitation (state of anxiety or nervous excitement): 7 people, 25.00%
Confusion: 7 people, 25.00%
Skin Discoloration - Bluish (bluish colour of skin): 7 people, 25.00%
Hyperhidrosis (abnormally increased sweating): 7 people, 25.00%
Dyspnea (difficult or laboured breathing): 5 people, 17.86%
Hepatic Necrosis (large portions of liver die off due to severe liver disease): 5 people, 17.86%
Hepatitis Fulminant (life-threatening condition defined by significantly impaired liver function): 5 people, 17.86%

What are the existing conditions these people have? *

Lipids Increased (excess lipid in body): 8 people, 28.57%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 17.86%
Depression: 5 people, 17.86%
Localised Osteoarthritis (infection of joint affects only single joint): 3 people, 10.71%
Depressed Mood: 3 people, 10.71%
Pain: 2 people, 7.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.14%
Dermatophytosis (inflammation of the skin and underlying muscle tissue): 1 person, 3.57%
Constipation: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Lorazepam and have Coma hepatic?

- Check whether Coma hepatic is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lorazepam:

Lorazepam (165,639 reports)

Coma hepatic treatments and more:

Coma hepatic (1,279 reports)

Browse all side effects of Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coma hepatic:

Coma hepatic (149 drugs)

Browse all the conditions that are associated with Coma hepatic:

Coma hepatic (409 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam (the active ingredients of Lorazepam) and Lorazepam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.