Lorazepam and Pick's disease - a phase IV clinical study of FDA data

Summary:

Pick's disease is reported as a side effect among people who take Lorazepam (lorazepam), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Valproate Sodium, and have Depression.

The phase IV clinical study analyzes which people have Pick's disease when taking Lorazepam. It is created by eHealthMe based on reports of 161,687 people who have side effects when taking Lorazepam from the FDA, and is updated regularly.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

What is Pick's disease?

Pick's disease (progressive dementia) is found to be associated with 36 drugs and 378 conditions by eHealthMe. Check the latest studies of Pick's disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 01, 2026

161,687 people reported to have side effects when taking Lorazepam.
Among them, 22 people (0.01%) have Pick's disease.

Among these 22 people:

How long have people been on Lorazepam when they have Pick's disease? *

What is the gender of people who have Pick's disease when taking Lorazepam? *

female: 31.25 %
male: 68.75 %

What is the age of people who have Pick's disease when taking Lorazepam? *

What are other drugs people take besides Lorazepam? *

Clorazepate Dipotassium: 4 people, 18.18%
Olanzapine: 4 people, 18.18%
Zaleplon: 4 people, 18.18%
Mirtazapine: 4 people, 18.18%
Sertraline Hydrochloride: 4 people, 18.18%
Valproate Sodium: 4 people, 18.18%
Oxycodone: 3 people, 13.64%
Colace: 3 people, 13.64%
Seroquel: 3 people, 13.64%
Sugammadex: 3 people, 13.64%

What are other side effects people have besides Pick's disease? *

Drug Ineffective: 9 people, 40.91%
Memory Loss: 6 people, 27.27%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 6 people, 27.27%
Depression: 4 people, 18.18%
Akathisia (a movement disorder characterized by a feeling of inner restlessness): 3 people, 13.64%
Hemiparesis (weakness on one side of the body): 3 people, 13.64%
Headache (pain in head): 3 people, 13.64%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 3 people, 13.64%
Fall: 3 people, 13.64%
Neurologic Neglect Syndrome (neuropsychological condition in which, after damage to one hemisphere of the brain is sustained, a deficit in attention to and awareness of one side of space is observed): 3 people, 13.64%

What are the existing conditions these people have? *

Depression: 5 people, 22.73%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 18.18%
Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 3 people, 13.64%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 9.09%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 9.09%
Agitation (state of anxiety or nervous excitement): 2 people, 9.09%
Parkinson's Disease: 2 people, 9.09%
Headache (pain in head): 2 people, 9.09%
Catatonia (unresponsive to external stimuli): 2 people, 9.09%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Lorazepam and have Pick's disease?

- Check whether Pick's disease is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lorazepam:

Lorazepam (165,639 reports)

Browse all side effects of Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pick's disease:

Pick's disease (36 drugs)

Browse all the conditions that are associated with Pick's disease:

Pick's disease (378 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam (the active ingredients of Lorazepam) and Lorazepam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.