Lortab and Gallbladder injury - a phase IV clinical study of FDA data

Summary:

Gallbladder injury is reported as a side effect among people who take Lortab (acetaminophen; hydrocodone bitartrate), especially for people who are female, 20-29 old, also take Yasmin, and have Birth control.

The phase IV clinical study analyzes which people have Gallbladder injury when taking Lortab. It is created by eHealthMe based on reports of 29,547 people who have side effects when taking Lortab from the FDA, and is updated regularly.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

What is Gallbladder injury?

Gallbladder injury is found to be associated with 213 drugs and 569 conditions by eHealthMe. Check the latest studies of Gallbladder injury.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

29,547 people reported to have side effects when taking Lortab.
Among them, 61 people (0.21%) have Gallbladder injury.

Among these 61 people:

What is the gender of people who have Gallbladder injury when taking Lortab? *

female: 98.36 %
male: 1.64 %

What is the age of people who have Gallbladder injury when taking Lortab? *

What are other drugs people take besides Lortab? *

Yasmin: 44 people, 72.13%
Yaz: 41 people, 67.21%
Phenergan: 13 people, 21.31%
Ibuprofen: 11 people, 18.03%
Drospirenone And Ethinyl Estradiol: 10 people, 16.39%
Hydrocodone Bitartrate And Acetaminophen: 9 people, 14.75%
Zoloft: 8 people, 13.11%
Zofran: 7 people, 11.48%
Percocet: 7 people, 11.48%
Naproxen: 7 people, 11.48%

What are other side effects people have besides Gallbladder injury? *

Cholecystitis Chronic (long lasting infection of gallbladder): 35 people, 57.38%
Injury: 29 people, 47.54%
Gallstones (stone formation by bile component): 15 people, 24.59%
Biliary Dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi): 12 people, 19.67%
Stress And Anxiety: 10 people, 16.39%
Emotional Distress: 9 people, 14.75%
Nausea And Vomiting: 9 people, 14.75%
Nausea (feeling of having an urge to vomit): 8 people, 13.11%
Abdominal Pain: 8 people, 13.11%
Diarrhea: 7 people, 11.48%

What are the existing conditions these people have? *

Birth Control: 16 people, 26.23%
Premenstrual Syndrome: 11 people, 18.03%
Stress And Anxiety: 8 people, 13.11%
Acne (skin problems that cause pimples): 5 people, 8.20%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 4 people, 6.56%
Depression: 4 people, 6.56%
Migraine (headache): 2 people, 3.28%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 3.28%
Dysmenorrhea (painful menstruation): 2 people, 3.28%
Heavy Or Prolong Menstrual Bleeding: 2 people, 3.28%

* Approximation only. Some reports may have incomplete information.

Do you take Lortab and have Gallbladder injury?

- Check whether Gallbladder injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lortab:

Lortab (31,285 reports)

Gallbladder injury treatments and more:

Gallbladder injury (4,397 reports)

How severe was Gallbladder injury and when was it recovered:

Gallbladder injury in Lortab

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Gallbladder injury and drugs with ingredients of acetaminophen; hydrocodone bitartrate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder injury:

Gallbladder injury (213 drugs)

Browse all the conditions that are associated with Gallbladder injury:

Gallbladder injury (569 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Lortab) and Lortab (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.