Losartan and Affective disorder - a phase IV clinical study of FDA data

Summary:

Affective disorder is reported as a side effect among people who take Losartan (losartan potassium), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Vitamin D3, and have Primary myelofibrosis.

The phase IV clinical study analyzes which people have Affective disorder when taking Losartan. It is created by eHealthMe based on reports of 170,768 people who have side effects when taking Losartan from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,692 Losartan users. Check the latest studies of Losartan.

What is Affective disorder?

Affective disorder (mental disorder) is found to be associated with 708 drugs and 785 conditions by eHealthMe. Check the latest studies of Affective disorder.

On Aug, 09, 2026

170,768 people reported to have side effects when taking Losartan.
Among them, 83 people (0.05%) have Affective disorder.

Could Losartan cause Affective disorder?

Among these 83 people:

How long have people been on Losartan when they have Affective disorder? *

What is the gender of people who have Affective disorder when taking Losartan? *

female: 60.29 %
male: 39.71 %

What is the age of people who have Affective disorder when taking Losartan? *

What are other drugs people take besides Losartan? *

What are other side effects people have besides Affective disorder? *

Dizziness: 37 people, 44.58%
Weakness: 35 people, 42.17%
Dyspnea (difficult or laboured breathing): 33 people, 39.76%
Fatigue (feeling of tiredness): 32 people, 38.55%
Weight Decreased: 32 people, 38.55%
Anaemia (lack of blood): 29 people, 34.94%
Depressed Mood: 29 people, 34.94%
Renal Disorder (kidney disease): 27 people, 32.53%
Urinary Tract Infection: 26 people, 31.33%
Hyperhidrosis (abnormally increased sweating): 26 people, 31.33%

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 24 people, 28.92%
Pain: 16 people, 19.28%
Anaemia (lack of blood): 12 people, 14.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 14.46%
High Blood Cholesterol: 11 people, 13.25%
Blood Uric Acid Abnormal: 8 people, 9.64%
Sleep Disorder: 8 people, 9.64%
Stress And Anxiety: 7 people, 8.43%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.23%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and have Affective disorder?

- Check whether Affective disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Losartan:

Losartan (177,692 reports)

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Affective disorder:

Affective disorder (708 drugs)

Browse all the conditions that are associated with Affective disorder:

Affective disorder (785 conditions)

Related publications that referenced our studies

Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Losartan) and Losartan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.