Lotrel and Increased upper airway secretion - a phase IV clinical study of FDA data

Summary:

Increased upper airway secretion is reported as a side effect among people who take Lotrel (amlodipine besylate; benazepril hydrochloride), especially for people who are female, 60+ old, also take Zoloft, and have Pain.

The phase IV clinical study analyzes which people have Increased upper airway secretion when taking Lotrel. It is created by eHealthMe based on reports of 13,000 people who have side effects when taking Lotrel from the FDA, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Increased upper airway secretion?

Increased upper airway secretion is found to be associated with 616 drugs and 627 conditions by eHealthMe. Check the latest studies of Increased upper airway secretion.

On Aug, 12, 2026

13,000 people reported to have side effects when taking Lotrel.
Among them, 20 people (0.15%) have Increased upper airway secretion.

Could Lotrel cause Increased upper airway secretion?

Among these 20 people:

What is the gender of people who have Increased upper airway secretion when taking Lotrel? *

female: 57.89 %
male: 42.11 %

What is the age of people who have Increased upper airway secretion when taking Lotrel? *

What are other drugs people take besides Lotrel? *

What are other side effects people have besides Increased upper airway secretion? *

Hypersensitivity: 5 people, 25.00%
Pain: 5 people, 25.00%
Breast Pain: 5 people, 25.00%
Drowsiness: 5 people, 25.00%
Increased Bronchial Secretion: 5 people, 25.00%
Prostatic Specific Antigen Increased: 5 people, 25.00%
Joint Pain: 5 people, 25.00%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 4 people, 20.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 15.00%
Breast Enlargement: 3 people, 15.00%

What are the existing conditions these people have? *

Pain: 5 people, 25.00%
Abdominal Discomfort: 4 people, 20.00%
Prostate Cancer: 4 people, 20.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 20.00%
Quit Smoking: 3 people, 15.00%
Prostatic Disorder: 3 people, 15.00%
Depression: 2 people, 10.00%
Back Pain: 2 people, 10.00%
Stress And Anxiety: 2 people, 10.00%
Nausea And Vomiting: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lotrel and have Increased upper airway secretion?

- Check whether Increased upper airway secretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lotrel:

Lotrel (13,571 reports)

Increased upper airway secretion treatments and more:

Increased upper airway secretion (6,962 reports)

How severe was Increased upper airway secretion and when was it recovered:

Increased upper airway secretion in Lotrel

Expand to all the drugs that have ingredients of amlodipine besylate; benazepril hydrochloride:

Increased upper airway secretion and drugs with ingredients of amlodipine besylate; benazepril hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lotrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Increased upper airway secretion:

Increased upper airway secretion (616 drugs)

Browse all the conditions that are associated with Increased upper airway secretion:

Increased upper airway secretion (627 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; benazepril hydrochloride (the active ingredients of Lotrel) and Lotrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.