Lotrel and Pleurisy - a phase IV clinical study of FDA data

Summary:

Pleurisy is reported as a side effect among people who take Lotrel (amlodipine besylate; benazepril hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Metastases to bone.

The phase IV clinical study analyzes which people have Pleurisy when taking Lotrel. It is created by eHealthMe based on reports of 13,000 people who have side effects when taking Lotrel from the FDA, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Pleurisy?

Pleurisy (inflammation of the pleurae, which causes pain when breathing) is found to be associated with 812 drugs and 1,141 conditions by eHealthMe. Check the latest studies of Pleurisy.

On Jul, 20, 2026

13,000 people reported to have side effects when taking Lotrel.
Among them, 14 people (0.11%) have Pleurisy.

Among these 14 people:

How long have people been on Lotrel when they have Pleurisy? *

What is the gender of people who have Pleurisy when taking Lotrel? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Pleurisy when taking Lotrel? *

What are other drugs people take besides Lotrel? *

Lasix: 6 people, 42.86%
Aspirin: 4 people, 28.57%
Ketorolac Tromethamine: 4 people, 28.57%
Ofloxacin: 4 people, 28.57%
Cosopt: 4 people, 28.57%
Prednisolone: 4 people, 28.57%
Zometa: 4 people, 28.57%
Zinc Sulfate: 3 people, 21.43%
Flonase: 3 people, 21.43%
Xanax: 3 people, 21.43%

What are other side effects people have besides Pleurisy? *

Chest Pain: 7 people, 50.00%
Dyspnea (difficult or laboured breathing): 7 people, 50.00%
Drug Hypersensitivity: 6 people, 42.86%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 35.71%
Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 35.71%
Fall: 5 people, 35.71%
Swollen Tongue (swelling of tongue): 5 people, 35.71%
Back Pain: 4 people, 28.57%
Sinusitis (inflammation of sinus): 4 people, 28.57%
Dizziness: 4 people, 28.57%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 3 people, 21.43%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 14.29%
Post-Traumatic Stress Disorder: 2 people, 14.29%
Osteoporosis (bones weak and more likely to break): 2 people, 14.29%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 14.29%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 14.29%
Bipolar Disorder (mood disorder): 2 people, 14.29%
Upper Respiratory Tract Infection: 1 person, 7.14%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 7.14%
Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Lotrel and have Pleurisy?

- Check whether Pleurisy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lotrel:

Lotrel (13,571 reports)

Pleurisy treatments and more:

Pleurisy (9,090 reports)

How severe was Pleurisy and when was it recovered:

Pleurisy in Lotrel

Expand to all the drugs that have ingredients of amlodipine besylate; benazepril hydrochloride:

Pleurisy and drugs with ingredients of amlodipine besylate; benazepril hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lotrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pleurisy:

Pleurisy (812 drugs)

Browse all the conditions that are associated with Pleurisy:

Pleurisy (1,141 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; benazepril hydrochloride (the active ingredients of Lotrel) and Lotrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.