Loxapine and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Loxapine (loxapine succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Valium, and have Schizophrenia.

The phase IV clinical study analyzes which people have Constipation when taking Loxapine. It is created by eHealthMe based on reports of 5,005 people who have side effects when taking Loxapine from the FDA, and is updated regularly.

What is Loxapine?

Loxapine has active ingredients of loxapine succinate. eHealthMe is studying from 5,039 Loxapine users. Check the latest studies of Loxapine.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,618 conditions by eHealthMe. Check the latest studies of Constipation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

5,005 people reported to have side effects when taking Loxapine.
Among them, 88 people (1.76%) have Constipation.

Among these 88 people:

How long have people been on Loxapine when they have Constipation? *

What is the gender of people who have Constipation when taking Loxapine? *

female: 59.3 %
male: 40.7 %

What is the age of people who have Constipation when taking Loxapine? *

What are other drugs people take besides Loxapine? *

What are other side effects people have besides Constipation? *

Weight Increased: 21 people, 23.86%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 17 people, 19.32%
Intestinal Obstruction: 17 people, 19.32%
Galactorrhea (secretion of breast milk in men): 15 people, 17.05%
Movement - Uncontrolled Or Slow: 14 people, 15.91%
Abdominal Pain: 14 people, 15.91%
Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 13 people, 14.77%
Weakness: 11 people, 12.50%
Fatigue (feeling of tiredness): 11 people, 12.50%
Amenorrhea (absence of a menstrual period in a woman of reproductive age): 11 people, 12.50%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 23 people, 26.14%
Agitation (state of anxiety or nervous excitement): 19 people, 21.59%
Insomnia (sleeplessness): 12 people, 13.64%
Bipolar Disorder (mood disorder): 12 people, 13.64%
Psychotic Disorder: 12 people, 13.64%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 11 people, 12.50%
Delusional Disorder, Unspecified Type: 9 people, 10.23%
Aggression: 9 people, 10.23%
Stress And Anxiety: 6 people, 6.82%
Pain: 5 people, 5.68%

* Approximation only. Some reports may have incomplete information.

Do you take Loxapine and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Loxapine:

Loxapine (5,039 reports)

Constipation treatments and more:

Constipation (337,880 reports)

Browse all side effects of Loxapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,618 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loxapine succinate (the active ingredients of Loxapine) and Loxapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.