Lubiprostone and Pain in extremity - a phase IV clinical study of FDA data

Summary:

Pain in extremity is reported as a side effect among people who take Lubiprostone (lubiprostone), especially for people who are female, 60+ old, also take Gabapentin, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Pain in extremity when taking Lubiprostone. It is created by eHealthMe based on reports of 952 people who have side effects when taking Lubiprostone from the FDA, and is updated regularly.

What is Lubiprostone?

Lubiprostone has active ingredients of lubiprostone. eHealthMe is studying from 957 Lubiprostone users. Check the latest studies of Lubiprostone.

What is Pain in extremity?

Pain in extremity is found to be associated with 3,223 drugs and 4,296 conditions by eHealthMe. Check the latest studies of Pain in extremity.



On Aug, 04, 2026

952 people reported to have side effects when taking Lubiprostone.
Among them, 18 people (1.89%) have Pain in extremity.

Could Lubiprostone cause Pain in extremity?

Among these 18 people:

What is the gender of people who have Pain in extremity when taking Lubiprostone? *

  • female: 83.33 %
  • male: 16.67 %

What is the age of people who have Pain in extremity when taking Lubiprostone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 18.75 %
  • 50-59: 37.5 %
  • 60+: 43.75 %

What are other drugs people take besides Lubiprostone? *

  1. Ondansetron: 5 people, 27.78%
  2. Pantoprazole: 5 people, 27.78%
  3. Gabapentin: 5 people, 27.78%
  4. Uptravi: 4 people, 22.22%
  5. Aspirin: 4 people, 22.22%
  6. Synthroid: 4 people, 22.22%
  7. Mirabegron: 4 people, 22.22%
  8. Vitamin D3: 4 people, 22.22%
  9. Vitamin C: 4 people, 22.22%
  10. Lisinopril: 3 people, 16.67%

What are other side effects people have besides Pain in extremity? *

  1. Joint Pain: 9 people, 50.00%
  2. Pain: 8 people, 44.44%
  3. Peripheral Swelling: 7 people, 38.89%
  4. Nausea (feeling of having an urge to vomit): 5 people, 27.78%
  5. Dizziness: 5 people, 27.78%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 5 people, 27.78%
  7. Diarrhea: 5 people, 27.78%
  8. Fever: 5 people, 27.78%
  9. Fatigue (feeling of tiredness): 5 people, 27.78%
  10. Muscle Spasms (muscle contraction): 5 people, 27.78%

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 22.22%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 16.67%
  3. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 16.67%
  4. Pain: 2 people, 11.11%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.11%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 11.11%
  7. Immunodeficiency Common Variable: 2 people, 11.11%
  8. Constipation: 2 people, 11.11%
  9. Stress And Anxiety: 1 person, 5.56%
  10. Gastric Disorder (disease of stomach): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Lubiprostone and have Pain in extremity?

- Check whether Pain in extremity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lubiprostone:

Pain in extremity treatments and more:

How severe was Pain in extremity and when was it recovered:

Expand to all the drugs that have ingredients of lubiprostone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lubiprostone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain in extremity:

Browse all the conditions that are associated with Pain in extremity:


How the study uses the data?

The study uses data from the FDA. It is based on lubiprostone (the active ingredients of Lubiprostone) and Lubiprostone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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