Lucentis and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Lucentis (ranibizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Benadryl, and have Asthma.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Lucentis. It is created by eHealthMe based on reports of 25,577 people who have side effects when taking Lucentis from the FDA, and is updated regularly.

What is Lucentis?

Lucentis has active ingredients of ranibizumab. It is often used in macular degeneration. eHealthMe is studying from 25,647 Lucentis users. Check the latest studies of Lucentis.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 2,011 drugs and 2,799 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

On Jan, 10, 2026

25,577 people reported to have side effects when taking Lucentis.
Among them, 23 people (0.09%) have Anaphylaxis.

Among these 23 people:

How long have people been on Lucentis when they have Anaphylaxis? *

What is the gender of people who have Anaphylaxis when taking Lucentis? *

female: 86.96 %
male: 13.04 %

What is the age of people who have Anaphylaxis when taking Lucentis? *

What are other drugs people take besides Lucentis? *

What are other side effects people have besides Anaphylaxis? *

Nausea And Vomiting: 6 people, 26.09%
Angioedema (rapid swelling of the dermis): 6 people, 26.09%
Urticaria (rash of round, red welts on the skin that itch intensely): 6 people, 26.09%
Diarrhea: 5 people, 21.74%
Injection Site Swelling: 5 people, 21.74%
Gastroenteritis Viral (inflammation of stomach and intestine caused by virus infection): 5 people, 21.74%
The Flu (the flu is caused by an influenza virus): 5 people, 21.74%
Swelling Face: 5 people, 21.74%
Dyspnea (difficult or laboured breathing): 4 people, 17.39%
Rashes (redness): 3 people, 13.04%

What are the existing conditions these people have? *

Asthma: 6 people, 26.09%
Age-Related Macular Degeneration: 2 people, 8.70%
Sleep Disorder: 2 people, 8.70%
High Blood Pressure: 1 person, 4.35%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 4.35%
Constipation: 1 person, 4.35%
Cough: 1 person, 4.35%
Diabetes: 1 person, 4.35%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 4.35%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Lucentis and have Anaphylaxis?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lucentis:

Lucentis (25,647 reports)

Anaphylaxis treatments and more:

Anaphylaxis (91,195 reports)

Browse all side effects of Lucentis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Anaphylaxis (2,011 drugs)

Browse all the conditions that are associated with Anaphylaxis:

Anaphylaxis (2,799 conditions)

Related publications that referenced our studies

An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .
An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on ranibizumab (the active ingredients of Lucentis) and Lucentis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.