Lucentis and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Lucentis (ranibizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Flagyl, and have Age-related macular degeneration.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Lucentis. It is created by eHealthMe based on reports of 25,577 people who have side effects when taking Lucentis from the FDA, and is updated regularly.

What is Lucentis?

Lucentis has active ingredients of ranibizumab. It is often used in macular degeneration. eHealthMe is studying from 25,647 Lucentis users. Check the latest studies of Lucentis.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,616 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

25,577 people reported to have side effects when taking Lucentis.
Among them, 15 people (0.06%) have Hypothyroidism.

Among these 15 people:

How long have people been on Lucentis when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Lucentis? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Hypothyroidism when taking Lucentis? *

What are other drugs people take besides Lucentis? *

Flagyl: 3 people, 20.00%
Eylea: 2 people, 13.33%
Dostinex: 1 person, 6.67%
Alendronate Sodium: 1 person, 6.67%
Amiodarone Hydrochloride: 1 person, 6.67%
Amlodipine: 1 person, 6.67%
Aricept: 1 person, 6.67%
Aspirin: 1 person, 6.67%
Avodart: 1 person, 6.67%
Benicar: 1 person, 6.67%

What are other side effects people have besides Hypothyroidism? *

Stress And Anxiety: 5 people, 33.33%
Feeling Abnormal: 4 people, 26.67%
Gait Disturbance: 3 people, 20.00%
Grip Strength Decreased: 3 people, 20.00%
Dyspnea (difficult or laboured breathing): 3 people, 20.00%
Dysaesthesia (abnormal sensation): 3 people, 20.00%
Hemiplegia (paralysis of one side of the body): 3 people, 20.00%
Muscle Aches (muscle pain): 3 people, 20.00%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 20.00%
Pain: 3 people, 20.00%

What are the existing conditions these people have? *

Vaginal Infection: 3 people, 20.00%
Retinopathy (acute damage to the retina of the eye): 3 people, 20.00%
Age-Related Macular Degeneration: 3 people, 20.00%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 13.33%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 13.33%
Retinal Neovascularisation (development of tiny, abnormal, leaky blood vessels inside the retina): 1 person, 6.67%
Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
High Blood Cholesterol: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lucentis and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lucentis:

Lucentis (25,647 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,067 reports)

Browse all side effects of Lucentis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,616 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on ranibizumab (the active ingredients of Lucentis) and Lucentis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.