Ludiomil and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Ludiomil (maprotiline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Anafranil, and have Depression.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Ludiomil. It is created by eHealthMe based on reports of 1,290 people who have side effects when taking Ludiomil from the FDA, and is updated regularly.

What is Ludiomil?

Ludiomil has active ingredients of maprotiline hydrochloride. eHealthMe is studying from 1,300 Ludiomil users. Check the latest studies of Ludiomil.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,836 drugs and 4,492 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

On Jul, 19, 2026

1,290 people reported to have side effects when taking Ludiomil.
Among them, 31 people (2.4%) have Acute kidney failure.

Could Ludiomil cause Acute kidney failure?

Among these 31 people:

How long have people been on Ludiomil when they have Acute kidney failure? *

What is the gender of people who have Acute kidney failure when taking Ludiomil? *

female: 64.52 %
male: 35.48 %

What is the age of people who have Acute kidney failure when taking Ludiomil? *

What are other drugs people take besides Ludiomil? *

Anafranil: 8 people, 25.81%
Seroquel: 7 people, 22.58%
Zoloft: 7 people, 22.58%
Amoxapine: 6 people, 19.35%
Sertraline: 4 people, 12.90%
Lasix: 4 people, 12.90%
Amitriptyline Hydrochloride: 3 people, 9.68%
Hyzaar: 3 people, 9.68%
Onglyza: 3 people, 9.68%
Trazodone Hydrochloride: 3 people, 9.68%

What are other side effects people have besides Acute kidney failure? *

Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 13 people, 41.94%
Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 8 people, 25.81%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 7 people, 22.58%
Blood Creatinine Increased: 7 people, 22.58%
Oedema Peripheral (superficial swelling): 7 people, 22.58%
Pancreatitis Acute (sudden inflammation of pancreas): 7 people, 22.58%
Weakness: 7 people, 22.58%
Blood Creatine Phosphokinase Increased: 6 people, 19.35%
Constipation: 5 people, 16.13%
Delirium (wild excitement): 5 people, 16.13%

What are the existing conditions these people have? *

Depression: 18 people, 58.06%
High Blood Pressure: 5 people, 16.13%
Sleep Disorder: 4 people, 12.90%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 3 people, 9.68%
Renal Impairment (severely reduced kidney function): 3 people, 9.68%
Insomnia (sleeplessness): 1 person, 3.23%
Adverse Event: 1 person, 3.23%
Arrhythmias (irregular heartbeat): 1 person, 3.23%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 1 person, 3.23%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Ludiomil and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ludiomil:

Ludiomil (1,300 reports)

Browse all side effects of Ludiomil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,836 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,492 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on maprotiline hydrochloride (the active ingredients of Ludiomil) and Ludiomil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.