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Ludiomil and Hyponatremia - a phase IV clinical study of FDA data

Summary:

Hyponatremia is reported as a side effect among people who take Ludiomil (maprotiline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Brintellix, and have Depression.

The phase IV clinical study analyzes which people have Hyponatremia when taking Ludiomil. It is created by eHealthMe based on reports of 1,290 people who have side effects when taking Ludiomil from the FDA, and is updated regularly.

What is Ludiomil?

Ludiomil has active ingredients of maprotiline hydrochloride. eHealthMe is studying from 1,300 Ludiomil users. Check the latest studies of Ludiomil.

What is Hyponatremia?

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,938 drugs and 2,272 conditions by eHealthMe. Check the latest studies of Hyponatremia.

On Jul, 15, 2026

1,290 people reported to have side effects when taking Ludiomil.
Among them, 82 people (6.36%) have Hyponatremia.

Could Ludiomil cause Hyponatremia?

Among these 82 people:

How long have people been on Ludiomil when they have Hyponatremia? *

  • < 1 month: 91.3 %
  • 1 - 6 months: 8.7 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyponatremia when taking Ludiomil? *

  • female: 76.54 %
  • male: 23.46 %

What is the age of people who have Hyponatremia when taking Ludiomil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.53 %
  • 30-39: 0.0 %
  • 40-49: 6.33 %
  • 50-59: 1.27 %
  • 60+: 89.87 %

What are other drugs people take besides Ludiomil? *

  1. Brintellix: 41 people, 50.00%
  2. Fluoxetine: 35 people, 42.68%
  3. Asenapine Maleate: 15 people, 18.29%
  4. Asenapine: 11 people, 13.41%
  5. Fluvoxamine Maleate: 7 people, 8.54%
  6. Alprazolam: 6 people, 7.32%
  7. Omeprazole: 4 people, 4.88%
  8. Iressa: 4 people, 4.88%
  9. Zyprexa: 4 people, 4.88%
  10. Clarithromycin: 3 people, 3.66%

What are other side effects people have besides Hyponatremia? *

  1. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 47 people, 57.32%
  2. Thirst - Excessive: 45 people, 54.88%
  3. Depressed Level Of Consciousness: 44 people, 53.66%
  4. Cardiac Arrest: 42 people, 51.22%
  5. Embolic Stroke (stroke due to obstruction due to an embolus): 39 people, 47.56%
  6. Respiration Abnormal (abnormal breathing process): 39 people, 47.56%
  7. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 39 people, 47.56%
  8. Delirium (wild excitement): 9 people, 10.98%
  9. Head Injury: 6 people, 7.32%
  10. Rashes (redness): 6 people, 7.32%

What are the existing conditions these people have? *

  1. Depression: 51 people, 62.20%
  2. Insomnia (sleeplessness): 6 people, 7.32%
  3. Lung Cancer - Non-Small Cell (lung cancer): 4 people, 4.88%
  4. Gastric Ulcer (stomach ulcer): 3 people, 3.66%
  5. Stress And Anxiety: 1 person, 1.22%
  6. High Blood Pressure: 1 person, 1.22%
  7. Depressive Delusion (a false belief or opinion due to depression): 1 person, 1.22%
  8. Delusion (a false belief or opinion): 1 person, 1.22%
  9. Agitation (state of anxiety or nervous excitement): 1 person, 1.22%

* Approximation only. Some reports may have incomplete information.

Do you take Ludiomil and have Hyponatremia?

- Check whether Hyponatremia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ludiomil:

Hyponatremia treatments and more:

How severe was Hyponatremia and when was it recovered:

Expand to all the drugs that have ingredients of maprotiline hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ludiomil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatremia:

Browse all the conditions that are associated with Hyponatremia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on maprotiline hydrochloride (the active ingredients of Ludiomil) and Ludiomil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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