Lyrica and Cheilitis - a phase IV clinical study of FDA data

Summary:

Cheilitis is reported as a side effect among people who take Lyrica (pregabalin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Back pain.

The phase IV clinical study analyzes which people have Cheilitis when taking Lyrica. It is created by eHealthMe based on reports of 255,839 people who have side effects when taking Lyrica from the FDA, and is updated regularly.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

What is Cheilitis?

Cheilitis (infection of lips) is found to be associated with 546 drugs and 910 conditions by eHealthMe. Check the latest studies of Cheilitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

255,839 people reported to have side effects when taking Lyrica.
Among them, 60 people (0.02%) have Cheilitis.

Among these 60 people:

How long have people been on Lyrica when they have Cheilitis? *

What is the gender of people who have Cheilitis when taking Lyrica? *

female: 84.48 %
male: 15.52 %

What is the age of people who have Cheilitis when taking Lyrica? *

What are other drugs people take besides Lyrica? *

What are other side effects people have besides Cheilitis? *

Rashes (redness): 20 people, 33.33%
Headache (pain in head): 14 people, 23.33%
Nausea (feeling of having an urge to vomit): 13 people, 21.67%
Fatigue (feeling of tiredness): 12 people, 20.00%
Lip Swelling: 10 people, 16.67%
Erythema Multiforme (a type of hypersensitivity reaction): 10 people, 16.67%
High Blood Pressure: 9 people, 15.00%
Dizziness: 9 people, 15.00%
Joint Pain: 9 people, 15.00%
Dry Mouth: 9 people, 15.00%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 6 people, 10.00%
Back Pain: 6 people, 10.00%
Colon Cancer: 5 people, 8.33%
High Blood Cholesterol: 4 people, 6.67%
Neuropathy Peripheral (surface nerve damage): 4 people, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 6.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.00%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 5.00%
Stress And Anxiety: 3 people, 5.00%
Depression: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lyrica and have Cheilitis?

- Check whether Cheilitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lyrica:

Lyrica (261,646 reports)

Cheilitis treatments and more:

Cheilitis (6,997 reports)

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cheilitis:

Cheilitis (546 drugs)

Browse all the conditions that are associated with Cheilitis:

Cheilitis (910 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Lyrica) and Lyrica (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.