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Lyrica and Electrocardiogram st segment depression - a phase IV clinical study of FDA data

Summary:

Electrocardiogram st segment depression is reported as a side effect among people who take Lyrica (pregabalin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Amlodipine Besylate, and have High blood pressure.

The phase IV clinical study analyzes which people have Electrocardiogram st segment depression when taking Lyrica. It is created by eHealthMe based on reports of 255,839 people who have side effects when taking Lyrica from the FDA, and is updated regularly.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

What is Electrocardiogram st segment depression?

Electrocardiogram st segment depression is found to be associated with 453 drugs and 677 conditions by eHealthMe. Check the latest studies of Electrocardiogram st segment depression.

On Jul, 07, 2026

255,839 people reported to have side effects when taking Lyrica.
Among them, 50 people (0.02%) have Electrocardiogram st segment depression.

Could Lyrica cause Electrocardiogram st segment depression?

Among these 50 people:

How long have people been on Lyrica when they have Electrocardiogram st segment depression? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Electrocardiogram st segment depression when taking Lyrica? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Electrocardiogram st segment depression when taking Lyrica? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 20.0 %
  • 30-39: 0.0 %
  • 40-49: 2.86 %
  • 50-59: 14.29 %
  • 60+: 62.86 %

What are other drugs people take besides Lyrica? *

  1. Amlodipine Besylate: 17 people, 34.00%
  2. Nexium: 11 people, 22.00%
  3. Pantoprazole Sodium: 11 people, 22.00%
  4. Valtrex: 11 people, 22.00%
  5. Digoxin: 10 people, 20.00%
  6. Protonix: 10 people, 20.00%
  7. Furosemide: 10 people, 20.00%
  8. Torsemide: 9 people, 18.00%
  9. Metformin Hydrochloride: 9 people, 18.00%
  10. Mcp: 9 people, 18.00%

What are other side effects people have besides Electrocardiogram st segment depression? *

  1. Chest Pain: 29 people, 58.00%
  2. Weakness: 23 people, 46.00%
  3. Fatigue (feeling of tiredness): 23 people, 46.00%
  4. Diarrhea: 21 people, 42.00%
  5. High Blood Pressure: 19 people, 38.00%
  6. Pain In Extremity: 17 people, 34.00%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 14 people, 28.00%
  8. Dizziness: 14 people, 28.00%
  9. Nausea (feeling of having an urge to vomit): 12 people, 24.00%
  10. Joint Pain: 12 people, 24.00%

What are the existing conditions these people have? *

  1. High Blood Pressure: 11 people, 22.00%
  2. Type 2 Diabetes: 9 people, 18.00%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 16.00%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 12.00%
  5. Dizziness: 6 people, 12.00%
  6. Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 12.00%
  7. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 5 people, 10.00%
  8. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 4.00%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.00%
  10. Cancer Pain: 1 person, 2.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lyrica and have Electrocardiogram st segment depression?

- Check whether Electrocardiogram st segment depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lyrica:

Electrocardiogram st segment depression treatments and more:

How severe was Electrocardiogram st segment depression and when was it recovered:

Expand to all the drugs that have ingredients of pregabalin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Electrocardiogram st segment depression:

Browse all the conditions that are associated with Electrocardiogram st segment depression:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Lyrica) and Lyrica (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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