Lyrica and Intervertebral disc compression - a phase IV clinical study of FDA data

Summary:

Intervertebral disc compression is reported as a side effect among people who take Lyrica (pregabalin), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Revlimid, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Intervertebral disc compression when taking Lyrica. It is created by eHealthMe based on reports of 255,839 people who have side effects when taking Lyrica from the FDA, and is updated regularly.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

What is Intervertebral disc compression?

Intervertebral disc compression (spinal disc compression) is found to be associated with 291 drugs and 286 conditions by eHealthMe. Check the latest studies of Intervertebral disc compression.

On Jul, 05, 2026

255,839 people reported to have side effects when taking Lyrica.
Among them, 57 people (0.02%) have Intervertebral disc compression.

Could Lyrica cause Intervertebral disc compression?

Among these 57 people:

How long have people been on Lyrica when they have Intervertebral disc compression? *

What is the gender of people who have Intervertebral disc compression when taking Lyrica? *

female: 52.73 %
male: 47.27 %

What is the age of people who have Intervertebral disc compression when taking Lyrica? *

What are other drugs people take besides Lyrica? *

What are other side effects people have besides Intervertebral disc compression? *

Intervertebral Disc Protrusion (spinal disc protrusion): 19 people, 33.33%
High Blood Pressure: 18 people, 31.58%
Neuropathy Peripheral (surface nerve damage): 17 people, 29.82%
Osteoporosis (bones weak and more likely to break): 16 people, 28.07%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 14 people, 24.56%
Multiple Myeloma (cancer of the plasma cells): 14 people, 24.56%
Osteopenia (a condition where bone mineral density is lower than normal): 14 people, 24.56%
Stress And Anxiety: 14 people, 24.56%
Cataract (clouding of the lens inside the eye): 14 people, 24.56%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 14 people, 24.56%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 19.30%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 10.53%
Osteoporosis (bones weak and more likely to break): 5 people, 8.77%
High Blood Pressure: 4 people, 7.02%
Depression: 3 people, 5.26%
Back Pain: 3 people, 5.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 5.26%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.26%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.26%
Bone Loss: 2 people, 3.51%

* Approximation only. Some reports may have incomplete information.

Do you take Lyrica and have Intervertebral disc compression?

- Check whether Intervertebral disc compression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lyrica:

Lyrica (261,646 reports)

Browse all side effects of Lyrica:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc compression:

Intervertebral disc compression (291 drugs)

Browse all the conditions that are associated with Intervertebral disc compression:

Intervertebral disc compression (286 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Lyrica) and Lyrica (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.