Mefloquine and Diarrhea - a phase IV clinical study of FDA data
Summary:
Diarrhea is reported as a side effect among people who take Mefloquine (mefloquine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Ibrutinib, and have Burkitt lymphoma.
The phase IV clinical study analyzes which people have Diarrhea when taking Mefloquine. It is created by eHealthMe based on reports of 899 people who have side effects when taking Mefloquine from the FDA, and is updated regularly.
What is Mefloquine?
Mefloquine has active ingredients of mefloquine hydrochloride. It is often used in malaria. eHealthMe is studying from 991 Mefloquine users. Check the latest studies of Mefloquine.
What is Diarrhea?
Diarrhea is found to be associated with 3,729 drugs and 5,751 conditions by eHealthMe. Check the latest studies of Diarrhea.
899 people reported to have side effects when taking Mefloquine.
Among them, 42 people (4.67%) have Diarrhea.

Among these 42 people:
How long have people been on Mefloquine when they have Diarrhea? *
- < 1 month: 43.75 %
- 1 - 6 months: 50.0 %
- 6 - 12 months: 6.25 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Diarrhea when taking Mefloquine? *
- female: 42.11 %
- male: 57.89 %
What is the age of people who have Diarrhea when taking Mefloquine? *
- 0-1: 0.0 %
- 2-9: 3.12 %
- 10-19: 6.25 %
- 20-29: 18.75 %
- 30-39: 18.75 %
- 40-49: 15.62 %
- 50-59: 6.25 %
- 60+: 31.25 %
What are other drugs people take besides Mefloquine? *
- Ibrutinib: 10 people, 23.81%
- Primaquine: 5 people, 11.90%
- Artesunate: 5 people, 11.90%
- Bendamustine: 2 people, 4.76%
- Xyrem: 1 person, 2.38%
- Diflucan: 1 person, 2.38%
- Azithromycin: 1 person, 2.38%
- Celebrex: 1 person, 2.38%
- Cipro: 1 person, 2.38%
- Dexilant: 1 person, 2.38%
What are other side effects people have besides Diarrhea? *
- Nausea And Vomiting: 14 people, 33.33%
- Nausea (feeling of having an urge to vomit): 12 people, 28.57%
- Drug Ineffective: 12 people, 28.57%
- Dizziness: 11 people, 26.19%
- Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 10 people, 23.81%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 23.81%
- Atypical Pneumonia (acute respiratory disease marked by high fever and coughing): 10 people, 23.81%
- Bone Marrow Failure: 10 people, 23.81%
- Hyperkeratosis (thickening of the outer layer of the skin): 10 people, 23.81%
- Headache (pain in head): 10 people, 23.81%
What are the existing conditions these people have? *
- Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 10 people, 23.81%
- Burkitt Lymphoma (cancer of the lymphatic system): 10 people, 23.81%
- Plasmodium Falciparum Infection (malaria caused by the protozoan parasite plasmodium falciparum): 4 people, 9.52%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 4.76%
- Sleep Disorder: 1 person, 2.38%
- Quit Smoking: 1 person, 2.38%
- Occupational Problem Environmental: 1 person, 2.38%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 2.38%
- Colitis (inflammation of colon): 1 person, 2.38%
- Adverse Event: 1 person, 2.38%
* Approximation only. Some reports may have incomplete information.
Do you take Mefloquine and have Diarrhea?
- Check whether Diarrhea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Mefloquine:
- Mefloquine (991 reports)
Diarrhea treatments and more:
- Diarrhea (756,290 reports)
How severe was Diarrhea and when was it recovered:
Expand to all the drugs that have ingredients of mefloquine hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mefloquine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Diarrhea:
- Diarrhea (3,729 drugs)
Browse all the conditions that are associated with Diarrhea:
- Diarrhea (5,751 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on mefloquine hydrochloride (the active ingredients of Mefloquine) and Mefloquine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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